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The Journal of Thoracic and Cardiovascular Surgery, Vol 102, 554-560, Copyright © 1991 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
J Amano and A Suzuki
Coronary artery disease is a rare involvement of Takayasu's arteritis. From
1961 to 1989, 63 patients, including our five, have been reported to
undergo operations for coronary artery disease resulting from Takayasu's
arteritis. Most of the patients were Japanese (86%) and female (86%). The
initial clinical manifestation was angina pectoris in 71%. Among 92
lesions, coronary ostia were most frequently involved (73%) followed by
nonostial proximal lesions (18.5%). Forty-two of 62 (67.7%) ostial lesions
of the left main coronary artery had more than 90%, or complete, stenosis.
Aortic regurgitation was associated in 28 patients (44.4%). Myocardial
revascularization was performed in 49, and transaortic endarterectomy in
12. Concomitant aortic valve replacement was done in 16 patients. Operative
mortality was five (7.9%), and late deaths were reported in three patients.
Postoperative steroid therapy was performed in 22. Operation was repeated
in two patients because of graft failure. Thus coronary artery disease
resulting from Takayasu's arteritis should be suspected in young Asian
women with angina pectoris. The timing preferred for surgical intervention
is during an inactive phase. Two procedures are commonly chosen for
surgical intervention, either transaortic endarterectomy or coronary
revascularization with vein grafts. Postoperative steroid therapy is
strongly recommended to those patients who are operated on in the
clinically or histologically active stage.
ARTICLES
Coronary artery involvement in Takayasu's arteritis. Collective review and guideline for surgical treatment
Department of Cardiothoracic Surgery, Tokyo Medical and Dental University, Japan.
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