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The Journal of Thoracic and Cardiovascular Surgery, Vol 103, 1104-1111, Copyright © 1992 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
CI Blauth, DM Cosgrove, BW Webb, NB Ratliff, M Boylan, MR Piedmonte, BW Lytle and FD Loop
As the ages of patients undergoing cardiac operations have increased,
noncardiac causes of death have increased. To identify these causes of
death, we analyzed the autopsy findings in 221 patients undergoing
myocardial revascularization or valve operations between 1982 and 1989.
Mean age was 65.6 +/- 9.5 years and the range was from 32 to 94 years; 130
patients (58.8%) were male. Autopsies were complete in 129 patients (58.4%)
and limited to the chest and abdomen in the remainder. Embolic disease was
identified in 69 patients (31.2%). Atheroemboli or abnormalities consistent
with atheroemboli were identified in 48 patients (21.7%). Fourteen patients
had thromboembolism and 7 had disseminated intravascular coagulation. The
prevalence of atheroembolic disease increased dramatically from 4.5% in
1982 to 48.3% in 1989 (p = 0.001). Atheroembolic disease was found in the
brain in 16.3% of patients, spleen in 10.9%, kidney in 10.4%, and pancreas
in 6.8%. Thirty (62.5%) of the 48 patients had multiple atheroembolic
sites. Atheroemboli were more common in patients undergoing coronary artery
procedures (43/165; 26.1%) than in those undergoing valve procedures (5/56;
8.9%) (p = 0.008). There was a high correlation of atheroemboli with severe
atherosclerosis of the ascending aorta. Atheroembolic events occurred in 46
of 123 patients (37.4%) with severe disease of the ascending aorta but in
only 2 of 98 patients (2%) without significant ascending aortic disease (p
less than 0.0001). Forty-six of 48 patients (95.8%) who had evidence of
atheroemboli had severe atherosclerosis of the ascending aorta. There was a
direct correlation between age, severe atherosclerosis of the ascending
aorta, and atheroemboli. Incremental risk factors for atheroembolic are
peripheral vascular disease and severe atherosclerosis of the ascending
aorta.
ARTICLES
Atheroembolism from the ascending aorta. An emerging problem in cardiac surgery
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, OH 44195-5066.
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V. G. Davila-Roman, N. T. Kouchoukos, K. B. Schechtman, and B. Barzilai ATHEROSCLEROSIS OF THE ASCENDING AORTA IS A PREDICTOR OF RENAL DYSFUNCTION AFTER CARDIAC OPERATIONS J. Thorac. Cardiovasc. Surg., January 1, 1999; 117(1): 111 - 116. [Abstract] [Full Text] [PDF] |
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R. C. King, R. C. Kanithanon, K. S. Shockey, W. D. Spotnitz, C. G. Tribble, and I. L. Kron Replacing the atherosclerotic ascending aorta is a high-risk procedure Ann. Thorac. Surg., August 1, 1998; 66(2): 396 - 401. [Abstract] [Full Text] [PDF] |
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E Ferrari, B Taillan, E Drai, P Morand, and M Baudouy Investigation of the thoracic aorta in cholesterol embolism by transoesophageal echocardiography Heart, February 1, 1998; 79(2): 133 - 136. [Abstract] [Full Text] |
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DavidP. Bichell, J. M. Balaguer, S. F. Aranki, G. S. Couper, D. H. Adams, R. J. Rizzo, J. J. Collins Jr, and L. H. Cohn Axilloaxillary Cardiopulmonary Bypass: A Practical Alternative to Femorofemoral Bypass Ann. Thorac. Surg., September 1, 1997; 64(3): 702 - 705. [Abstract] [Full Text] |
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D. Barbut, Y.-W. Lo, G. S. Hartman, F.-S. F. Yao, R. R. Trifiletti, D. N. Hager, R. B. Hinton, J. P. Gold, and O. W. Isom Aortic Atheroma Is Related to Outcome but Not Numbers of Emboli During Coronary Bypass Ann. Thorac. Surg., August 1, 1997; 64(2): 454 - 459. [Abstract] [Full Text] |
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N. T. Kouchoukos and D. Dougenis Surgery of the Thoracic Aorta N. Engl. J. Med., June 26, 1997; 336(26): 1876 - 1889. [Full Text] [PDF] |
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J. W. Hammon Jr, D. A. Stump, N. D. Kon, A. R. Cordell, A. S. Hudspeth, T. E. Oaks, R. F. Brooker, A. T. Rogers, R. Hilbawi, L. H. Coker, et al. Risk Factors and Solutions for the Development of Neurobehavioral Changes After Coronary Artery Bypass Grafting Ann. Thorac. Surg., June 1, 1997; 63(6): 1613 - 1617. [Abstract] [Full Text] |
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N. M. Katz and G. A. Chase Risks of Cardiac Operations for Elderly Patients: Reduction of the Age Factor Ann. Thorac. Surg., May 1, 1997; 63(5): 1309 - 1314. [Abstract] [Full Text] |
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L. Shore-Lesserson and S. N. Konstadt Aortic Atherosclerosis: Should We Bother to Look for It? Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 1997; 1(1): 39 - 48. [PDF] |
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C. T. Mora, M. B. Henson, W. S. Weintraub, J. M. Murkin, T. D. Martin, J. M. Craver, J. P. Gott, and R. A. Guyton THE EFFECT OF TEMPERATURE MANAGEMENT DURING CARDIOPULMONARY BYPASS ON NEUROLOGIC AND NEUROPSYCHOLOGIC OUTCOMES IN PATIENTS UNDERGOING CORONARY REVASCULARIZATION J. Thorac. Cardiovasc. Surg., August 1, 1996; 112(2): 514 - 522. [Abstract] [Full Text] |
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R. M. Bojar, D. D. Payne, R. E. Murphy, S. L. Schwartz, J. R. Belden, L. R. Caplan, and H. Rastegar Surgical Treatment of Systemic Atheroembolism From the Thoracic Aorta Ann. Thorac. Surg., May 1, 1996; 61(5): 1389 - 1393. [Abstract] [Full Text] |
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D. D. Muehrcke, R. A. Grimm, S. E. Nissen, and D. M. Cosgrove III Recurrent Cerebral Vascular Accidents Are an Indication for Ascending Aortic Endarterectomy Ann. Thorac. Surg., May 1, 1996; 61(5): 1516 - 1518. [Abstract] [Full Text] |
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R. C. Groom, A. G. Hill, B. F. Akl, A. M. Speir, P. S. Massimiano, E. A. Lefrak, D. D. Muehrcke, and D. M. Cosgrove III Cannula Length and Arch Flow Erosion Ann. Thorac. Surg., February 1, 1996; 61(2): 773 - 774. [Full Text] |
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R. C Groom, A. G Hill, B. Kuban, W. Oneill, B. F Akl, A. M Speir, J. Koningsberg, G. T Sprissler, M. Shakoor, P. S Massimiano, et al. Aortic cannula velocimetry Perfusion, May 1, 1995; 10(3): 183 - 188. [PDF] |
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S. A. Mills Risk Factors for Cerebral Injury and Cardiac Surgery Ann. Thorac. Surg., May 1, 1995; 59(5): 1296 - 1299. [Abstract] [Full Text] |
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C. I. Blauth Macroemboli and Microemboli During Cardiopulmonary Bypass Ann. Thorac. Surg., May 1, 1995; 59(5): 1300 - 1303. [Abstract] [Full Text] |
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M. F. Newman, N. D. Croughwell, J. A. Blumenthal, E. Lowry, W. D. White, W. Spillane, R. D. Davis Jr, D. D. Glower, L. R. Smith, E. P. Mahanna, et al. Predictors of Cognitive Decline After Cardiac Operation Ann. Thorac. Surg., May 1, 1995; 59(5): 1326 - 1330. [Abstract] [Full Text] |
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C. S. Rihal, K. A. Eagle, M. C. Mickel, E. D. Foster, G. Sopko, and B. J. Gersh Surgical Therapy for Coronary Artery Disease Among Patients With Combined Coronary Artery and Peripheral Vascular Disease Circulation, January 1, 1995; 91(1): 46 - 53. [Abstract] [Full Text] |
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