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The Journal of Thoracic and Cardiovascular Surgery, Vol 103, 1104-1111, Copyright © 1992 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association


ARTICLES

Atheroembolism from the ascending aorta. An emerging problem in cardiac surgery

CI Blauth, DM Cosgrove, BW Webb, NB Ratliff, M Boylan, MR Piedmonte, BW Lytle and FD Loop
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, OH 44195-5066.

As the ages of patients undergoing cardiac operations have increased, noncardiac causes of death have increased. To identify these causes of death, we analyzed the autopsy findings in 221 patients undergoing myocardial revascularization or valve operations between 1982 and 1989. Mean age was 65.6 +/- 9.5 years and the range was from 32 to 94 years; 130 patients (58.8%) were male. Autopsies were complete in 129 patients (58.4%) and limited to the chest and abdomen in the remainder. Embolic disease was identified in 69 patients (31.2%). Atheroemboli or abnormalities consistent with atheroemboli were identified in 48 patients (21.7%). Fourteen patients had thromboembolism and 7 had disseminated intravascular coagulation. The prevalence of atheroembolic disease increased dramatically from 4.5% in 1982 to 48.3% in 1989 (p = 0.001). Atheroembolic disease was found in the brain in 16.3% of patients, spleen in 10.9%, kidney in 10.4%, and pancreas in 6.8%. Thirty (62.5%) of the 48 patients had multiple atheroembolic sites. Atheroemboli were more common in patients undergoing coronary artery procedures (43/165; 26.1%) than in those undergoing valve procedures (5/56; 8.9%) (p = 0.008). There was a high correlation of atheroemboli with severe atherosclerosis of the ascending aorta. Atheroembolic events occurred in 46 of 123 patients (37.4%) with severe disease of the ascending aorta but in only 2 of 98 patients (2%) without significant ascending aortic disease (p less than 0.0001). Forty-six of 48 patients (95.8%) who had evidence of atheroemboli had severe atherosclerosis of the ascending aorta. There was a direct correlation between age, severe atherosclerosis of the ascending aorta, and atheroemboli. Incremental risk factors for atheroembolic are peripheral vascular disease and severe atherosclerosis of the ascending aorta.


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M. A. Ozatik, K. M Vural, E. Sener, and O. Tasdemir
Epiaortic Ultrasound: Aortic Screening in Coronary Revascularization
Asian Cardiovasc Thorac Ann, September 1, 1999; 7(3): 168 - 172.
[Abstract] [Full Text] [PDF]


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Eur. J. Cardiothorac. Surg.Home page
Y. Okita, M. Ando, K. Minatoya, O. Tagusari, S. Kitamura, N. Nakajjma, and S. Takamoto
Early and long-term results of surgery for aneurysms of the thoracic aorta in septuagenarians and octogenarians
Eur. J. Cardiothorac. Surg., September 1, 1999; 16(3): 317 - 323.
[Abstract] [Full Text] [PDF]


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StrokeHome page
S. Kilminster, T. Treasure, T. McMillan, and D. W. Holt
Neuropsychological Change and S-100 Protein Release in 130 Unselected Patients Undergoing Cardiac Surgery
Stroke, September 1, 1999; 30(9): 1869 - 1874.
[Abstract] [Full Text] [PDF]


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CirculationHome page
C. W. Hogue Jr, S. F. Murphy, K. B. Schechtman, and V. G. Davila-Roman
Risk Factors for Early or Delayed Stroke After Cardiac Surgery
Circulation, August 10, 1999; 100(6): 642 - 647.
[Abstract] [Full Text] [PDF]


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CirculationHome page
C. S. Rihal, K. Sutton-Tyrrell, P. Guo, N. M. Keller, R. Jandova, M. A. Sellers, H. V. Schaff, and D. R. Holmes Jr
Increased Incidence of Periprocedural Complications Among Patients With Peripheral Vascular Disease Undergoing Myocardial Revascularization in the Bypass Angioplasty Revascularization Investigation
Circulation, July 13, 1999; 100(2): 171 - 177.
[Abstract] [Full Text] [PDF]


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Ann. Thorac. Surg.Home page
O. A. Selnes, M. A. Goldsborough, L. M. Borowicz Jr, C. Enger, S. A. Quaskey, and G. M. McKhann
Determinants of cognitive change after coronary artery bypass surgery: a multifactorial problem
Ann. Thorac. Surg., June 1, 1999; 67(6): 1669 - 1676.
[Abstract] [Full Text] [PDF]


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Ann. Thorac. Surg.Home page
R. G. Leyh, C. Bartels, A. Notzold, and H.-H. Sievers
Management of porcelain aorta during coronary artery bypass grafting
Ann. Thorac. Surg., April 1, 1999; 67(4): 986 - 988.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
V. G. Davila-Roman, S. F. Murphy, N. J. Nickerson, N. T. Kouchoukos, K. B. Schechtman, and B. Barzilai
Atherosclerosis of the ascending aorta is an independent predictor of long-term neurologic events and mortality
J. Am. Coll. Cardiol., April 1, 1999; 33(5): 1308 - 1316.
[Abstract] [Full Text] [PDF]


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SEMIN CARDIOTHORAC VASC ANESTHHome page
J. M. Murkin
Strategies and Techniques for Neuroprotection in Coronary Artery Surgery
Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 1999; 3(1): 4 - 8.
[Abstract] [PDF]


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SEMIN CARDIOTHORAC VASC ANESTHHome page
C. W. Hogue JR, B. Barzilai, and V. G. Davila-Roman
Stroke Reduction: Diagnosis and Management of the Atherosclerotic Ascending Aorta During Cardiac Surgery
Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 1999; 3(1): 17 - 24.
[Abstract] [PDF]


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Ann. Thorac. Surg.Home page
P. R. Vogt, M. Hauser, U. Schwarz, R. Jenni, M. L. Lachat, G. Zund, R. W. Schupbach, D. Schmidlin, and M. I. Turina
Complete thromboendarterectomy of the calcified ascending aorta and aortic arch
Ann. Thorac. Surg., February 1, 1999; 67(2): 457 - 461.
[Abstract] [Full Text] [PDF]


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Ann. Thorac. Surg.Home page
M. Ura, R. Sakata, Y. Nakayama, T.-A. Miyamoto, and T. Goto
Extracorporeal circulation before and after ultrasonographic evaluation of the ascending aorta
Ann. Thorac. Surg., February 1, 1999; 67(2): 478 - 483.
[Abstract] [Full Text] [PDF]


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Ann. Thorac. Surg.Home page
Y. Okita, M. Ando, K. Minatoya, S. Kitamura, S. Takamoto, and N. Nakajima
Predictive factors for mortality and cerebral complications in arteriosclerotic aneurysm of the aortic arch
Ann. Thorac. Surg., January 1, 1999; 67(1): 72 - 78.
[Abstract] [Full Text] [PDF]


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J. Thorac. Cardiovasc. Surg.Home page
V. G. Davila-Roman, N. T. Kouchoukos, K. B. Schechtman, and B. Barzilai
ATHEROSCLEROSIS OF THE ASCENDING AORTA IS A PREDICTOR OF RENAL DYSFUNCTION AFTER CARDIAC OPERATIONS
J. Thorac. Cardiovasc. Surg., January 1, 1999; 117(1): 111 - 116.
[Abstract] [Full Text] [PDF]


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Ann. Thorac. Surg.Home page
R. C. King, R. C. Kanithanon, K. S. Shockey, W. D. Spotnitz, C. G. Tribble, and I. L. Kron
Replacing the atherosclerotic ascending aorta is a high-risk procedure
Ann. Thorac. Surg., August 1, 1998; 66(2): 396 - 401.
[Abstract] [Full Text] [PDF]


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HeartHome page
E Ferrari, B Taillan, E Drai, P Morand, and M Baudouy
Investigation of the thoracic aorta in cholesterol embolism by transoesophageal echocardiography
Heart, February 1, 1998; 79(2): 133 - 136.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
DavidP. Bichell, J. M. Balaguer, S. F. Aranki, G. S. Couper, D. H. Adams, R. J. Rizzo, J. J. Collins Jr, and L. H. Cohn
Axilloaxillary Cardiopulmonary Bypass: A Practical Alternative to Femorofemoral Bypass
Ann. Thorac. Surg., September 1, 1997; 64(3): 702 - 705.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
D. Barbut, Y.-W. Lo, G. S. Hartman, F.-S. F. Yao, R. R. Trifiletti, D. N. Hager, R. B. Hinton, J. P. Gold, and O. W. Isom
Aortic Atheroma Is Related to Outcome but Not Numbers of Emboli During Coronary Bypass
Ann. Thorac. Surg., August 1, 1997; 64(2): 454 - 459.
[Abstract] [Full Text]


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NEJMHome page
N. T. Kouchoukos and D. Dougenis
Surgery of the Thoracic Aorta
N. Engl. J. Med., June 26, 1997; 336(26): 1876 - 1889.
[Full Text] [PDF]


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Ann. Thorac. Surg.Home page
J. W. Hammon Jr, D. A. Stump, N. D. Kon, A. R. Cordell, A. S. Hudspeth, T. E. Oaks, R. F. Brooker, A. T. Rogers, R. Hilbawi, L. H. Coker, et al.
Risk Factors and Solutions for the Development of Neurobehavioral Changes After Coronary Artery Bypass Grafting
Ann. Thorac. Surg., June 1, 1997; 63(6): 1613 - 1617.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
N. M. Katz and G. A. Chase
Risks of Cardiac Operations for Elderly Patients: Reduction of the Age Factor
Ann. Thorac. Surg., May 1, 1997; 63(5): 1309 - 1314.
[Abstract] [Full Text]


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SEMIN CARDIOTHORAC VASC ANESTHHome page
L. Shore-Lesserson and S. N. Konstadt
Aortic Atherosclerosis: Should We Bother to Look for It?
Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 1997; 1(1): 39 - 48.
[PDF]


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J. Thorac. Cardiovasc. Surg.Home page
C. T. Mora, M. B. Henson, W. S. Weintraub, J. M. Murkin, T. D. Martin, J. M. Craver, J. P. Gott, and R. A. Guyton
THE EFFECT OF TEMPERATURE MANAGEMENT DURING CARDIOPULMONARY BYPASS ON NEUROLOGIC AND NEUROPSYCHOLOGIC OUTCOMES IN PATIENTS UNDERGOING CORONARY REVASCULARIZATION
J. Thorac. Cardiovasc. Surg., August 1, 1996; 112(2): 514 - 522.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
R. M. Bojar, D. D. Payne, R. E. Murphy, S. L. Schwartz, J. R. Belden, L. R. Caplan, and H. Rastegar
Surgical Treatment of Systemic Atheroembolism From the Thoracic Aorta
Ann. Thorac. Surg., May 1, 1996; 61(5): 1389 - 1393.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
D. D. Muehrcke, R. A. Grimm, S. E. Nissen, and D. M. Cosgrove III
Recurrent Cerebral Vascular Accidents Are an Indication for Ascending Aortic Endarterectomy
Ann. Thorac. Surg., May 1, 1996; 61(5): 1516 - 1518.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
R. C. Groom, A. G. Hill, B. F. Akl, A. M. Speir, P. S. Massimiano, E. A. Lefrak, D. D. Muehrcke, and D. M. Cosgrove III
Cannula Length and Arch Flow Erosion
Ann. Thorac. Surg., February 1, 1996; 61(2): 773 - 774.
[Full Text]


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PerfusionHome page
R. C Groom, A. G Hill, B. Kuban, W. Oneill, B. F Akl, A. M Speir, J. Koningsberg, G. T Sprissler, M. Shakoor, P. S Massimiano, et al.
Aortic cannula velocimetry
Perfusion, May 1, 1995; 10(3): 183 - 188.
[PDF]


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Ann. Thorac. Surg.Home page
S. A. Mills
Risk Factors for Cerebral Injury and Cardiac Surgery
Ann. Thorac. Surg., May 1, 1995; 59(5): 1296 - 1299.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
C. I. Blauth
Macroemboli and Microemboli During Cardiopulmonary Bypass
Ann. Thorac. Surg., May 1, 1995; 59(5): 1300 - 1303.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
M. F. Newman, N. D. Croughwell, J. A. Blumenthal, E. Lowry, W. D. White, W. Spillane, R. D. Davis Jr, D. D. Glower, L. R. Smith, E. P. Mahanna, et al.
Predictors of Cognitive Decline After Cardiac Operation
Ann. Thorac. Surg., May 1, 1995; 59(5): 1326 - 1330.
[Abstract] [Full Text]


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CirculationHome page
C. S. Rihal, K. A. Eagle, M. C. Mickel, E. D. Foster, G. Sopko, and B. J. Gersh
Surgical Therapy for Coronary Artery Disease Among Patients With Combined Coronary Artery and Peripheral Vascular Disease
Circulation, January 1, 1995; 91(1): 46 - 53.
[Abstract] [Full Text]




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