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The Journal of Thoracic and Cardiovascular Surgery, Vol 104, 434-442, Copyright © 1992 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
R McKay, A Smith, MP Leung, R Arnold and RH Anderson
The clinical presentation of infants with critical aortic stenosis, as well
as the results of surgical treatment, differs from obstruction of the left
ventricular outflow tract in older children. To investigate a possible
anatomic basis for this situation, we performed a detailed morphometric
study of 21 hearts from infants who had critical aortic stenosis and 11
normal hearts from infants less than 3 months of age. In each of the hearts
with critical aortic stenosis, only one commissure extended to the
sinutubular ridge. The other two commissures were represented by folds in
the aortic wall that suspended the leaflet below the level of the
sinutubular junction. The leaflet thus had a free edge shorter than the
circumference of the sinus, in contrast with the normal valve, in which
leaflets always were longer than the circumference of their supporting
sinus. Analysis of the fibrous triangles on the ventricular aspect of
abnormal valves showed a symmetric three-sinus arrangement. In all but one
specimen, however, only the triangle related to the mitral valve was fully
developed. Although incision of both rudimentary commissures to the aortic
wall should achieve some relief of obstruction, these morphologic features
strongly mitigate against surgical restoration of normal function or growth
in aortic valves having the morphology observed in this series of hearts.
ARTICLES
Morphology of the ventriculoaortic junction in critical aortic stenosis. Implications for hemodynamic function and clinical management
Royal Liverpool Children's Hospital, England.
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