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The Journal of Thoracic and Cardiovascular Surgery, Vol 105, 9-14, Copyright © 1993 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
G Massard, M Badier, C Guillot, M Reynaud, P Thomas, R Giudicelli and M Noirclerc
The present study evaluates the accuracy of submammary thoracic perimeter
for lung size matching between donor and recipient and analyzes the
influence of donor lung size discrepancies on functional outcome after
double lung transplantation. The population is composed of 18 double lung
graft recipients, 16 of whom had cystic fibrosis. The lung size match was
assessed by comparison of predicted total lung capacity of donor and
recipient: five patients were matched in a 10% confidence interval; four
received smaller lungs, and nine received larger ones. The functional
outcome was assessed with the spirometric values measured at 3 and 6 months
after transplantation. The final functional result was not influenced by
the lung size (r = 0.142 for total lung capacity; r = 0.372 for vital
capacity; r = 0.378 for forced expiratory volume in 1 second). For larger
lungs the final result tended to the recipient's predicted, whereas for
smaller lungs, spirometry tended to the donor's predicted (r = 0.906 for
total lung capacity; r = 0.875 for vital capacity; r = 0.874 for forced
expiratory volume in 1 second). The thoracotomy effect, that is,
restrictive syndrome at 3 months that resolves at 6 months, was not
correlated with the lung size (r = 0.07 for total lung capacity; r = 0.436
for vital capacity). It is concluded that respiratory functional result is
not affected by larger lungs; despite the wide range of error, the
submammary thoracic perimeter appeared to be a satisfactory selection
parameter in this group of patients.
ARTICLES
Lung size matching for double lung transplantation based on the submammary thoracic perimeter. Accuracy and functional results. The Joint Marseille-Montreal Lung Transplant Program
Service de Chirurgie Thoracique et Transplantations, Hopital Sainte Marguerite, Marseille, France.
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