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The Journal of Thoracic and Cardiovascular Surgery, Vol 105, 321-326, Copyright © 1993 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
M Pasic, T Carrel, L von Segesser and M Turina
Between 1969 and 1990 six patients (aged 14 to 64 years, mean 43 years)
underwent in situ reconstruction for mycotic aneurysm of the ascending
aorta. The primary source of infection was endocarditis in three patients
(subacute bacterial endocarditis [n = one patient], sepsis with acute
endocarditis [n = one patient]), sepsis with sternal osteomyelitis in one,
sepsis with purulent pericarditis in one, and generalized febrile illness
in one. In five of six patients the treatment consisted of the excision of
changed tissue combined with a composite graft (n = one patient), a
xenopericardial patch repair (n = one patient), a Dacron graft repair and
aortic valve replacement (n = one patient), a Dacron graft repair alone (n
= one patient), and a lateral suture combined with double valve replacement
(n = one patient). In one patient with perforation of the mycotic aneurysm
into the pulmonary artery, the place of rupture was oversewn without
excision of the aortic or pulmonary artery tissue. Two patients with local
pericardial inflammation were reoperated on during the hospital stay; one
of them because of recurrent mycotic aneurysm of the ascending aorta at the
other location and the other because of infection of the suture line after
the Dacron patch repair. Antibiotic therapy was intravenously administered
for 2 to 12 weeks postoperatively and continued orally for 4 to 8 weeks.
The mean observation time was 6 years (range 4 months to 16 years). There
was no late graft infection, except the chronic infection of the suture
line in one patient who died suddenly 4 months after the operation. There
was no early death, and there were three late deaths (chronic myocardial
failure, one patient, chronic renal failure, one patient, sudden death, one
patient). We concluded that in situ reconstruction for mycotic aneurysm of
the ascending aorta combined with prolonged antibiotic therapy is an
appropriate procedure with satisfactory early and good long-term results.
ARTICLES
In situ repair of mycotic aneurysm of the ascending aorta
Clinic for Cardiovascular Surgery, University Hospital Zurich, Switzerland.
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