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The Journal of Thoracic and Cardiovascular Surgery, Vol 105, 1047-1056, Copyright © 1993 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
FL Hanley, MK Heinemann, RA Jonas, JE Mayer Jr, NR Cook, DL Wessel and AR Castaneda
From September 1986 through December 1991, 63 patients with truncus
arteriosus underwent surgical repair. The management approach evolved over
the period of the study from elective primary repair at 3 months of age to
elective primary repair in the early neonatal period. Thirty variables were
examined as potential risk factors for the outcome events of death,
reoperation, and presence of pulmonary vascular morbidity. According to
both univariate and multivariate techniques, severe truncal valve
regurgitation, interrupted aortic arch, coronary artery anomalies, and age
at repair greater than 100 days were important risk factors for
perioperative death. In the 33 patients without these risk factors, early
survival was 100%. In the 30 patients with one or more of these risk
factors, survival was 63%. Pulmonary hypertensive episodes were fewer, and
duration of ventilator dependence and pulmonary artery pressure were
significantly less in patients undergoing the operation before 30 days of
age. Seven patients required reoperation for right ventricular outflow
tract obstruction at a mean follow-up time of 23.4 months, with no deaths.
In conclusion, interrupted aortic arch, severe truncal valve insufficiency,
coronary anomalies, and repair later than 100 days of age were risk factors
for death after repair of truncus arteriosus. In the absence of these
associations, truncus arteriosus can be repaired with excellent surgical
outcome in the neonatal and early infancy period. Repair in the early
neonatal period reduces the prevalence of postoperative pulmonary vascular
morbidity.
ARTICLES
Repair of truncus arteriosus in the neonate
Department of Cardiovascular Surgery, Harvard Medical School, Children's Hospital of Boston, Mass.
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