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The Journal of Thoracic and Cardiovascular Surgery, Vol 106, 444-448, Copyright © 1993 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association


ARTICLES

Clinical significance of weight difference between donor and recipient in heart transplantation

GK Sethi, P Lanauze, LJ Rosado, C Huston, MS McCarthy, S Butman and JG Copeland
Division of Cardiovascular and Thoracic Surgery, University of Arizona Heart Center, Tucson 85724.

A standard and important criterion for donor acceptance is to match the donor's body weight to within 20% of the recipient's body weight. However, to meet the increasing demand of patients who need heart transplantation, frequently a heart that is below the standard criteria for donation is accepted. Of the 200 consecutive patients who underwent heart transplantation at the University of Arizona, 27 patients received a heart from a smaller donor with a weight difference of more than 30% (range 30% to 46%). The early mortality and late survival of these 27 patients were not different when compared with those of the patients who received transplants from donors with a weight difference of less than 30%. The probability of freedom from rejection and infection and postoperative ejection fraction were also similar between the two groups. Therefore, we believe that the widely accepted donor- recipient weight-match criterion of 20% can be safely extended.


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