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J Thorac Cardiovasc Surg 1994;107:381-0393
© 1994 Mosby, Inc.

Surgery for Acquired Heart Disease

Determinants of reoperation after 960 valve replacements with Carpentier-Edwards prostheses

Durham, N.C.

From the Departments of Surgery and Community and Family Medicine, Duke University Medical Center, Durham, N.C.

Address for reprints: Donald D. Glower, MD, Box 3851, Duke University Medical Center, Durham, NC 27704.

Abstract

During the period of 1977 to 1990, 960 Carpentier-Edwards standard prostheses (Baxter Healthcare Corp., Santa Ana, Calif.) were placed in 875 operations. Freedom from reoperation at 10 years was 57% ± 4%, 76% ± 3%, and 95% ± 5% for mitral, aortic, and tricuspid valve replacement, respectively. Age was the only independent determinant of reoperation for both aortic and mitral valves. Likelihood of reoperation decreased with age, with freedom from reoperation after 10 years in patients aged less than 60 years versus 60 or more years being 65% ± 5% versus 90% ± 4% after aortic valve replacement and 48% ± 5% versus 75% ± 6% after mitral valve replacement. For mitral valve replacement, larger valve size made reoperation more likely, with freedom from reoperation at 10 years being 71% ± 6% for sizes less than 31 mm and 57% ± 5% for sizes 31 mm or larger. For aortic valve replacement, prior median sternotomy reduced freedom from reoperation at 10 years from 80% ± 3% to 25% ± 5%. The low prevalence of reoperation affirms the suitability of the Carpentier-Edwards prosthesis for selected elderly patients and for tricuspid valve replacement. Because of their influence on the probability of reoperation, valve size and prior cardiac procedures also merit consideration in the choice of valvular prosthesis. (J THORAC CARDIOVASC SURG 1994;107:381-93)

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