| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Thorac Cardiovasc Surg 1994;107:1337-1345
© 1994 Mosby, Inc.
CARDIAC AND PULMONARY REPLACEMENT |
Ann Arbor, Mich.
From the Section of Thoracic Surgery,a Department of Surgery, the Department of Radiology,b and the Division of Pulmonary Medicine,c Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich.
Address for reprints: Louis A. Brunsting, MD, The University of Michigan Hospitals, Section of Thoracic Surgery, 1500 E. Medical Center Dr., Ann Arbor, MI 48109-0344.
Abstract
The primary determinants of pulmonary function after heart-lung or double lung transplantation are the volume and compliance of the recipient's thoracic cage. This study evaluated the influence of recipient chest wall factors on static and dynamic lung volumes after single lung transplantation for chronic obstructive pulmonary disease. Fourteen patients with chronic obstructive pulmonary disease received 15 single lung transplants (one retransplant). Posttransplantation follow-up data at 3 and 6 months, in the absence of infection or rejection, were available in nine patients. Overall pulmonary function at 6 months improved from preoperative levels to 55% to 65% of predicted values (forced vital capacity 38% to 55%, forced expiratory volume at 1 second 18% to 55%, maximum voluntary ventilation 21% to 65%), and allograft-specific pulmonary function improved to nearly normal predicted single-lung values (forced vital capacity 89%, forced expiratory volume at 1 second 90%, maximum voluntary ventilation 105%). Postoperative pulmonary function in these patients correlated significantly with preoperative thoracic volume measured by planimetry of chest radiographs. No correlation between postoperative pulmonary function was demonstrated with either the estimated volume of donated lung tissue or relative donor-to-recipient size matching. These findings support the concept that recipient chest wall factors determine postoperative pulmonary function in patients undergoing single lung transplantation for chronic obstructive pulmonary disease. Furthermore, the allograft lung functions at a normal level for the recipient and does not appear to be constrained by hyperinflation of the contralateral lung. (J THORACCARDIOVASCSURG1994;107:1337-45)
This article has been cited by other articles:
|
|
 |
|
  S. H. Loring, S. J. Mentzer, and J. J. Reilly Sources of graft restriction after single lung transplantation for emphysema J. Thorac. Cardiovasc. Surg., July 1, 2007; 134(1): 204 - 209. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Lando, P. Boiselle, D. Shade, J. M. Travaline, S. Furukawa, and G. J. Criner Effect of Lung Volume Reduction Surgery on Bony Thorax Configuration in Severe COPD Chest, July 1, 1999; 116(1): 30 - 39. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. ESTENNE, M. CASSART, P. PONCELET, and P. A. GEVENOIS Volume of Graft and Native Lung after Single-Lung Transplantation for Emphysema Am. J. Respir. Crit. Care Med., February 1, 1999; 159(2): 641 - 645. [Abstract] [Full Text]
|
|
|
|
 |
|
 T. J. Kroshus, R. M. Bolman III, and V. R. Kshettry Unilateral Volume Reduction After Single-Lung Transplantation for Emphysema Ann. Thorac. Surg., August 1, 1996; 62(2): 363 - 368. [Abstract] [Full Text]
|
|
|
|
|
|
Contralateral Pneumonectomy After Single-Lung Transplantation for Emphysema Ann. Thorac. Surg., April 1, 1996; 61(4): 1286 - 1287. [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
