HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ashour, M. Search for Related Content PubMed PubMed Citation Articles by Ashour, M.

J Thorac Cardiovasc Surg 1995;109:632-635
© 1995 Mosby, Inc.

GENERAL THORACIC SURGERY

Prevalence of ectopic thymic tissue in myasthenia gravis and its clinical significance

Riyadh, Saudi Arabia

From King Khalid University Hospital, Riyadh, Saudi Arabia.

Received for publication April 29, 1994. Accepted for publication Sept. 29, 1994. Address for reprints: Mahmoud H. Ashour, FRCS, Associate Professor, Thoracic Surgery, King Khalid University Hospital, P.O. Box 7805, Riyadh 11472, Saudi Arabia.

Abstract

Forty patients with myasthenia gravis underwent maximal thymectomy. Complete histologic study findings were available for 38 patients. The prevalence of ectopic thymic tissue was 39.5% (15 of 38). On the basis of the presence or absence of ectopic thymic tissue, patients were divided into two groups: group I had ectopic thymic tissue and group II had no ectopic thymic tissue. Male/female ratio was almost equal (1.1:1) in group I, whereas in group II the ratio was 1:2.8. The duration of the disease was less than 1 year in 80% of group I and 47.8% of group II patients (p = 0.05). Furthermore, ectopic thymic tissue (group I) was associated with poor outcome of operation (p = 0.003). Only 2 (13.3%) of 15 patients in group I had complete remission as compared with 11 (47.8%) of 23 patients in group II. Thus it appears that the presence of ectopic thymic tissue not only modifies some of the clinical parameters of myasthenia gravis, but also could serve as a prognostic factor in predicting the outcome of operation. (J THORAC CARDIOVASC SURG 1995;109:632-5)

This article has been cited by other articles:

				C. Prokakis, E. Koletsis, S. Salakou, E. Apostolakis, N. Baltayiannis, A. Chatzimichalis, T. Papapetropoulos, and D. Dougenis Modified maximal thymectomy for myasthenia gravis: effect of maximal resection on late neurologic outcome and predictors of disease remission. Ann. Thorac. Surg., November 1, 2009; 88(5): 1638 - 1645. [Abstract] [Full Text] [PDF]

				E. Pompeo, F. Tacconi, R. Massa, D. Mineo, S. Nahmias, and T. C. Mineo Long-term outcome of thoracoscopic extended thymectomy for nonthymomatous myasthenia gravis Eur. J. Cardiothorac. Surg., July 1, 2009; 36(1): 164 - 169. [Abstract] [Full Text] [PDF]

				H. Sakurai, M. Kaji, and K. Suemasu Thymoma of the Middle Mediastinum: 11C-Acetate Positron Emission Tomography Imaging Ann. Thorac. Surg., April 1, 2009; 87(4): 1271 - 1274. [Abstract] [Full Text] [PDF]

				J. M. Ponseti, J. Gamez, R. Vilallonga, C. Ruiz, J. Azem, M. Lopez-Cano, and M. Armengol Influence of ectopic thymic tissue on clinical outcome following extended thymectomy in generalized seropositive nonthymomatous myasthenia gravis Eur. J. Cardiothorac. Surg., November 1, 2008; 34(5): 1062 - 1067. [Abstract] [Full Text] [PDF]

				H. El-Bawab, A. A. Al-Sugair, M. Rafay, W. Hajjar, M. Mahdy, and K. Al-Kattan Role of flourine-18 fluorodeoxyglucose positron emission tomography in thymic pathology Eur. J. Cardiothorac. Surg., April 1, 2007; 31(4): 731 - 736. [Abstract] [Full Text] [PDF]

				J. Dooley, M. Erickson, G. O. Gillard, and A. G. Farr Cervical Thymus in the Mouse. J. Immunol., June 1, 2006; 176(11): 6484 - 6490. [Abstract] [Full Text] [PDF]

				F. Rea, G. Marulli, L. Bortolotti, P. Feltracco, A. Zuin, and F. Sartori Experience With the "Da Vinci" Robotic System for Thymectomy in Patients With Myasthenia Gravis: Report of 33 Cases Ann. Thorac. Surg., February 1, 2006; 81(2): 455 - 459. [Abstract] [Full Text] [PDF]

				M. Zielinski, J. Kuzdzal, and T. Nabialek Transcervical-subxiphoid-VATS "maximal" thymectomy for myasthenia gravis MMCTS, April 25, 2005; 2005(0425): 836. [Abstract] [Full Text] [PDF]

				M. Zielinski, J. Kuzdzal, A. Szlubowski, and J. Soja Transcervical-subxiphoid-videothoracoscopic "maximal" thymectomy--operative technique and early results Ann. Thorac. Surg., August 1, 2004; 78(2): 404 - 409. [Abstract] [Full Text] [PDF]

				M. Zielinski, J. Kuzdzal, A. Szlubowski, and J. Soja Comparison of late results of basic transsternal and extended transsternal thymectomies in the treatment of myasthenia gravis Ann. Thorac. Surg., July 1, 2004; 78(1): 253 - 258. [Abstract] [Full Text] [PDF]

				M. Kanzaki, K. Oyama, T. Ikeda, T. Yoshida, M. Murasugi, and T. Onuki Noninvasive thymoma in the middle mediastinum Ann. Thorac. Surg., June 1, 2004; 77(6): 2209 - 2210. [Abstract] [Full Text] [PDF]

				Y. El-Medany, W. Hajjar, M. Essa, K. Al-Kattan, Z. Hariri, and M. Ashour Predictors of Outcome for Myasthenia Gravis after Thymectomy Asian Cardiovasc Thorac Ann, December 1, 2003; 11(4): 323 - 327. [Abstract] [Full Text] [PDF]

				M. Essa, Y. El-Medany, W. Hajjar, Z. Hariri, F. Al-Mulhim, M. Salih, M. Ashour, and K. Al-Kattan Maximal thymectomy in children with myasthenia gravis Eur. J. Cardiothorac. Surg., August 1, 2003; 24(2): 187 - 191. [Abstract] [Full Text] [PDF]

				N. Ozdemir, M. Kara, E. Dikmen, A. Nadir, M. Akal, N. Yucemen, and S. Yavuzer Predictors of clinical outcome following extended thymectomy in myasthenia gravis Eur. J. Cardiothorac. Surg., February 1, 2003; 23(2): 233 - 237. [Abstract] [Full Text] [PDF]

				K. Kojima, K. Yokoi, H. Matsuguma, T. Kondo, Y. Kamiyama, K. Mori, and S. Igarashi Middle mediastinal thymoma J. Thorac. Cardiovasc. Surg., September 1, 2002; 124(3): 639 - 640. [Full Text] [PDF]

				T. Roth, R. Ackermann, R. Stein, R. Inderbitzi, K. Rosler, and R.A. Schmid Thirteen years follow-up after radical transsternal thymectomy for myasthenia gravis. Do short-term results predict long-term outcome? Eur. J. Cardiothorac. Surg., April 1, 2002; 21(4): 664 - 670. [Abstract] [Full Text] [PDF]

				T. C. Mineo, E. Pompeo, T. E. Lerut, G. Bernardi, W. Coosemans, and I. Nofroni Thoracoscopic thymectomy in autoimmune myasthenia: results of left-sided approach Ann. Thorac. Surg., May 1, 2000; 69(5): 1537 - 1541. [Abstract] [Full Text] [PDF]

				I. P. Nieto, M. C. Pajuelo, and J. P. P. Robledo Reply Ann. Thorac. Surg., January 1, 2000; 69(1): 314 - 315. [Full Text] [PDF]

				J. I. Jung, H. H. Kim, S. H. Park, and Y. S. Lee Malignant Ectopic Thymoma in the Neck: A Case Report AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1747 - 1749. [Abstract] [Full Text]

				I. P. Nieto, J. P. P. Robledo, M. C. Pajuelo, J. A. R. Montes, J. G. Giron, J. G. Alonso, and L. G. Sancho Prognostic factors for myasthenia gravis treated by thymectomy: review of 61 cases Ann. Thorac. Surg., June 1, 1999; 67(6): 1568 - 1571. [Abstract] [Full Text] [PDF]