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The Journal of Thoracic and Cardiovascular Surgery, Vol 109, Issue 5 877-883, Copyright © 1995 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
NOTE: The fulltext of this article is not available online.
D. D. Glower, W. D. White, L. R. Smith, W. G. Young, H. N. Oldham, W. G. Wolfe and J. E. Lowe
Porcine bioprostheses are often used for tricuspid valve replacement, yet
the long-term outcome after this procedure is not well documented.
Therefore, the records of 129 patients undergoing tricuspid valve
replacement with Carpentier-Edwards (n = 88) or Hancock (n = 41) prostheses
between 1975 and 1993 were reviewed. The operation required a repeat median
sternotomy in 66 of 129 (51%) patients, whereas 67 of 129 (52%) underwent
double or triple valve replacement. Operative mortality was 14% (2/14) in
patients undergoing first-time isolated tricuspid valve replacement and 27%
(35/129) overall. Survival at 5, 10, and 14 years was 56% +/- 5%, 48% +/-
5%, and 31% +/- 9%, and freedom from tricuspid reoperation at 5, 10, and 14
years was 96% +/- 3%, 93% +/- 4%, and 49% +/- 17%. No valve thrombosis was
observed. In this largest reported series of porcine bioprostheses in the
tricuspid position, long-term freedom from valve-related events was
excellent because of a low incidence of valve thrombosis and a valve
durability of 13 to 15 years in a population with limited life expectancy.
CLINICAL TRIAL
In-hospital and long-term outcome after porcine tricuspid valve replacement
Department of Surgery, Duke University Medical Center, Durham, N.C. 27710, USA.
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