| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Thorac Cardiovasc Surg 1996;111:85-95
© 1996 Mosby, Inc.
GENERAL THORACIC SURGERY |
Leuven, Belgium
From the Department of Thoracic Surgery, University Hospitals, Leuven, Belgium.
Address for reprints: T. Lerut, MD, Department General Thoracic Surgery, Catholic University of Leuven, U.Z. Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.
Abstract
From 1983 to 1989, 95 patients with carcinoma of the esophagogastric junction underwent resection. Overall hospital mortality rate was 6.2% (6/95). Actuarial survival analysis showed 5- and 10-year survivals of 33% and 31%, respectively. Five- and 10-year survivals of patients according to TNM stages were as follows: stage I (n= 13), 90% at both 5 and 10 years; stage II (n= 13), 70% at both intervals; stage III (n= 28), 28% at both intervals; and stage IV (n= 40), 11% and 8%, respectively. For patients with undiseased nodes (n= 26), 5- and 10-year survivals were 72% and 72%, compared with 18% and 16% for patients with diseased nodes (n= 68; p< 0.005). In patients who had involvement of both the abdominal and thoracic lymph nodes (n= 28), 5- and 10-year survivals were 13% and 13%, compared with 26% and 26% if metastases were confined to the abdomen (n= 37; p> 0.05). Grouping patients with diseased intrathoracic nodes together with patients with N2 abdominal nodes showed survivals of 14% at both 5 and 10 years. When tumors were staged as an esophageal carcinoma, classification of individual patients changed, as did the 5- and 10-year survivals. Five- and 10-year survivals were as follows: stage I (n= 8), 100% for both 5 and 10 years; stage II (n= 18), 68% for both 5 and 10 years; stage III (n= 27), 37% for both 5 and 10 years; and stage IV (n= 41), 10% for 5 years and 6% for 10 years. These data indicate that tumors of the esophagogastric junction tend to spread to both abdominal and thoracic nodes. However, reasonably good 5- and 10-year survivals can be obtained even in patients with nodal metastases in both areas. We suggest that N2 labeling be included for thoracic node metastases instead of the actual M+Ly label, because the N2 label better reflects the potential for curative surgery. Finally, staging tumors as gastric or esophageal carcinoma makes no significant difference in survival analysis, which raises the question whether these tumors behave more like esophageal carcinoma than gastric carcinoma.
This article has been cited by other articles:
|
|
 |
|
  S. S. Lee, S.-B. Kim, S.-I. Park, Y. H. Kim, J.-S. Ryu, H.-Y. Song, J. H. Shin, H. Y. Jung, G. H. Lee, K. D. Choi, et al. Capecitabine and Cisplatin Chemotherapy (XP) Alone or Sequentially Combined Chemoradiotherapy Containing XP Regimen in Patients with Three Different Settings of Stage IV Esophageal Cancer Jpn. J. Clin. Oncol., November 1, 2007; 37(11): 829 - 835. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. F. Bruzzi, R. F. Munden, M. T. Truong, E. M. Marom, B. S. Sabloff, G. W. Gladish, R. B. Iyer, T.-S. Pan, H. A. Macapinlac, and J. J. Erasmus PET/CT of Esophageal Cancer: Its Role in Clinical Management RadioGraphics, November 1, 2007; 27(6): 1635 - 1652. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Hofstetter, A. M. Correa, N. Bekele, J. A. Ajani, A. Phan, R. R. Komaki, Z. Liao, D. Maru, T. T. Wu, R. J. Mehran, et al. Proposed Modification of Nodal Status in AJCC Esophageal Cancer Staging System Ann. Thorac. Surg., August 1, 2007; 84(2): 365 - 375. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Pedrazzani, G. de Manzoni, D. Marrelli, S. Giacopuzzi, G. Corso, A. M. Minicozzi, B. Rampone, and F. Roviello Lymph node involvement in advanced gastroesophageal junction adenocarcinoma J. Thorac. Cardiovasc. Surg., August 1, 2007; 134(2): 378 - 385. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. F. Onate-Ocana, G. Milan-Revollo, V. Aiello-Crocifoglio, J. F. Carrillo, D. Gallardo-Rincon, R. Brom-Valladares, R. Herrera-Goepfert, and A. Duenas-Gonzalez Treatment of the Adenocarcinoma of the Esophagogastric Junction at a Single Institution in Mexico Ann. Surg. Oncol., April 1, 2007; 14(4): 1439 - 1448. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y.-G. Goan, H.-C. Chang, H.-K. Hsu, and Y.-P. Chou An audit of surgical outcomes of esophageal squamous cell carcinoma Eur. J. Cardiothorac. Surg., March 1, 2007; 31(3): 536 - 544. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Lagarde, F. J.W. ten Kate, J. B. Reitsma, O. R.C. Busch, and J. J. B. van Lanschot Prognostic Factors in Adenocarcinoma of the Esophagus or Gastroesophageal Junction J. Clin. Oncol., September 10, 2006; 24(26): 4347 - 4355. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. G. Gaca, R. P. Petersen, B. L. Peterson, D. H. Harpole Jr., T. A. D'Amico, T. N. Pappas, H. F. Seigler, W. G. Wolfe, and D. S. Tyler Pathologic Nodal Status Predicts Disease-Free Survival After Neoadjuvant Chemoradiation for Gastroesophageal Junction Carcinoma Ann. Surg. Oncol., March 1, 2006; 13(3): 340 - 346. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. C. Malaisrie, W. L. Hofstetter, A. M. Correa, J. A. Ajani, R. R. Komaki, Z. Liao, A. Phan, D. C. Rice, A. A. Vaporciyan, G. L. Walsh, et al. Endoscopic ultrasonography-identified celiac adenopathy remains a poor prognostic factor despite preoperative chemoradiotherapy in esophageal adenocarcinoma J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 65 - 72. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Lee, K.-E. Lee, Y.-H. Im, W. K. Kang, K. Park, K. Kim, and Y. M. Shim Adjuvant Chemotherapy with 5-Fluorouracil and Cisplatin in Lymph Node-Positive Thoracic Esophageal Squamous Cell Carcinoma Ann. Thorac. Surg., October 1, 2005; 80(4): 1170 - 1175. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. R. Chirieac, S. G. Swisher, A. M. Correa, J. A. Ajani, R. R. Komaki, A. Rashid, S. R. Hamilton, and T.-T. Wu Signet-Ring Cell or Mucinous Histology after Preoperative Chemoradiation and Survival in Patients with Esophageal or Esophagogastric Junction Adenocarcinoma Clin. Cancer Res., March 15, 2005; 11(6): 2229 - 2236. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. A. Marsman, R. S. Birjmohun, B. P. van Rees, E. Caspers, G. Johan, A. Offerhaus, P. J. Bosma, J. Jan, and B. van Lanschot Loss of Heterozygosity and Immunohistochemistry of Adenocarcinomas of the Esophagus and Gastric Cardia Clin. Cancer Res., December 15, 2004; 10(24): 8479 - 8485. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C J Buskens, A Sivula, B P van Rees, C Haglund, G J A Offerhaus, J J B van Lanschot, and A Ristimaki Comparison of cyclooxygenase 2 expression in adenocarcinomas of the gastric cardia and distal oesophagus Gut, December 1, 2003; 52(12): 1678 - 1683. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Goldberg, J. Farma, C. Lampert, P. Colarusso, L. Coia, H. Frucht, E. Goosenberg, M. Beard, and L. M. Weiner Survival following intensive preoperative combined modality therapy with paclitaxel, cisplatin, 5-fluorouracil, and radiation in resectable esophageal carcinoma: A phase I report J. Thorac. Cardiovasc. Surg., October 1, 2003; 126(4): 1168 - 1173. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Hagen and T. R. DeMeester Staging of esophageal carcinoma J. Thorac. Cardiovasc. Surg., May 1, 2003; 125(5): 988 - 991. [Full Text] [PDF]
|
|
|
|
|
|
T. W. Rice, E. H. Blackstone, L. A. Rybicki, D. J. Adelstein, S. C. Murthy, M. M. DeCamp, and J. R. Goldblum Refining esophageal cancer staging J. Thorac. Cardiovasc. Surg., May 1, 2003; 125(5): 1103 - 1113. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. G. Casson, S. C. Evans, A. Gillis, G. A. Porter, P. Veugelers, S. J. Darnton, D. L. Guernsey, and P. Hainaut Clinical implications of p53 tumor suppressor gene mutation and protein expression in esophageal adenocarcinomas: Results of a ten-year prospective study J. Thorac. Cardiovasc. Surg., May 1, 2003; 125(5): 1121 - 1131. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. B.F. Hulscher, J. W. van Sandick, A. G.E.M. de Boer, B. P.L. Wijnhoven, J. G.P. Tijssen, P. Fockens, P. F.M. Stalmeier, F. J.W. ten Kate, H. van Dekken, H. Obertop, et al. Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus N. Engl. J. Med., November 21, 2002; 347(21): 1662 - 1669. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Schroder, S.P. Monig, S.E. Baldus, C. Gutschow, P.M. Schneider, and A.H. Holscher Frequency of Nodal Metastases to the Upper Mediastinum in Barrett's Cancer Ann. Surg. Oncol., October 1, 2002; 9(8): 807 - 811. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Raja, J. D. Luketich, L. A. Kelly, W. E. Gooding, S. D. Finkelstein, and T. E. Godfrey Rapid, quantitative reverse transcriptase-polymerase chain reaction: Application to intraoperative molecular detection of occult metastases in esophageal cancer J. Thorac. Cardiovasc. Surg., March 1, 2002; 123(3): 475 - 483. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. E. Godfrey, S. Raja, S. D. Finkelstein, W. E. Gooding, L. A. Kelly, and J. D. Luketich Prognostic Value of Quantitative Reverse Transcription-Polymerase Chain Reaction in Lymph Node-negative Esophageal Cancer Patients Clin. Cancer Res., December 1, 2001; 7(12): 4041 - 4048. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Jiao, M. J. Krasna, J. Sonett, Z. Gamliel, M. Suntharalingam, A. Doyle, and B. Greenwald Pretreatment surgical lymph node staging predicts results of trimodality therapy in esophageal cancer Eur. J. Cardiothorac. Surg., June 1, 2001; 19(6): 880 - 886. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. G. Casson, S. J. Darnton, S. Subramanian, and L. Hiller What is the optimal distal resection margin for esophageal carcinoma? Ann. Thorac. Surg., January 1, 2000; 69(1): 205 - 209. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Lerut, W. Coosemans, P. De Leyn, D. Van Raemdonck, G. Deneffe, and G. Decker Treatment of Esophageal Carcinoma* Chest, December 1, 1999; 116(suppl_3): 463S - 465S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. A. Christie, T. W. Rice, M. M. DeCamp, J. R. Goldblum, D. J. Adelstein, G. Zuccaro Jr, L. A. Rybicki, and E. H. Blackstone M1A/M1B ESOPHAGEAL CARCINOMA: CLINICAL RELEVANCE J. Thorac. Cardiovasc. Surg., November 1, 1999; 118(5): 900 - 907. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Luketich, D. M. Friedman, T. L. Weigel, M. A. Meehan, R. J. Keenan, D. W. Townsend, and C. C. Meltzer Evaluation of distant metastases in esophageal cancer: 100 consecutive positron emission tomography scans Ann. Thorac. Surg., October 1, 1999; 68(4): 1133 - 1136. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. van de Ven, P. De Leyn, W. Coosemans, D. Van Raemdonck, and T. Lerut Three-field lymphadenectomy and pattern of lymph node spread in T3 adenocarcinoma of the distal esophagus and the gastro-esophageal junction Eur. J. Cardiothorac. Surg., June 1, 1999; 15(6): 769 - 773. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J.R. Dalrymple-Hay, K. B. Evans, and R. E. Lea Oesophagectomy for carcinoma of the oesophagus and oesophagogastric junction Eur. J. Cardiothorac. Surg., May 1, 1999; 15(5): 626 - 630. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Lerut Esophageal surgery at the end of the millennium J. Thorac. Cardiovasc. Surg., July 1, 1998; 116(1): 1 - 20. [Full Text]
|
|
|
|
|
|
R. J. Korst, V. W. Rusch, E. Venkatraman, M. S. Bains, M. E. Burt, R. J. Downey, and R. J. Ginsberg Proposed Revision Of The Staging Classification For Esophageal Cancer J. Thorac. Cardiovasc. Surg., March 1, 1998; 115(3): 660 - 670. [Abstract] [Full Text]
|
|
|
|
|
|
J. D. Luketich, P. Schauer, R. Landreneau, N. Nguyen, K. Urso, P. Ferson, R. Keenan, and R. Kim MINIMALLY INVASIVE SURGICAL STAGING IS SUPERIOR TO ENDOSCOPIC ULTRASOUND IN DETECTING LYMPH NODE METASTASES IN ESOPHAGEAL CANCER J. Thorac. Cardiovasc. Surg., November 1, 1997; 114(5): 817 - 823. [Abstract] [Full Text]
|
|
|
|
|
|
R. Bardini and M. J. Krasna Thoracoscopic staging of esophageal cancer: a prospective, multiinstitutional trial. Ann. Thorac. Surg., October 1, 1996; 62(4): 1237 - 1239. [Full Text]
|
|
|
|
|
|
H. Wilke and U. Fink Multimodal Therapy for Adenocarcinoma of the Esophagus and Esophagogastric Junction N. Engl. J. Med., August 15, 1996; 335(7): 509 - 510. [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
