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J Thorac Cardiovasc Surg 1996;111:784-790
© 1996 Mosby, Inc.


CARDIAC AND PULMONARY REPLACEMENT

CONTINUOUS WARM REPERFUSION DURING HEART TRANSPLANTATION

Gonzalo Pradas, MDa, Jose Cuenca, MD, Alberto Juffé, MDb

Received for publication August 19, 1994 Accepted for publication June 7, 1995. Address for reprints: Gonzalo Pradas, MD, Unidad de Cirugía Cardíaca "Cardiovigo," Hospital do Meixoeiro, Apdo. Oficial s/n, 36200—Vigo, Pontevedra, Spain.

Abstract

From April 1991 to January 1993, 37 orthotopic heart transplantations were performed at our institution. Conventional preservation technique with cold crystalloid cardioplegia and topical hypothermia during storage and implantation was used in the first 15 cases (group A). After January 1992, for the next 22 patients (group B), we administered a first dose of hyperkalemic blood cardioplegia on arrival of the graft and thereafter instituted continuous warm reperfusion by infusion of oxygenated blood with added potassium. The groups were compared retrospectively, and significant differences were observed. In group B, the ischemic time was shortened by 31 minutes, the suture time lasted 12 minutes longer, sinus rhythm recovered spontaneously, the duration of inotropic support was reduced, postoperative arrythmias decreased, length of intensive care and hospital stays were reduced, there was less ischemic damage in the first endomyocardial biopsy sample, and right ventricular pressures a month after operation were lower. Continuous warm reperfusion during implantation of the donor heart is technically feasible and seems to provide enhanced myocardial preservation. (J THORACCARDIOVASCSURG1996;111:784-90)




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J. Thorac. Cardiovasc. Surg.Home page
G. B. Luciani, G. Faggian, G. Montalbano, G. Casali, A. Forni, B. Chiominto, and A. Mazzucco
BLOOD VERSUS CRYSTALLOID CARDIOPLEGIA FOR MYOCARDIAL PROTECTION OF DONOR HEARTS DURING TRANSPLANTATION: A PROSPECTIVE, RANDOMIZED CLINICAL TRIAL
J. Thorac. Cardiovasc. Surg., November 1, 1999; 118(5): 787 - 795.
[Abstract] [Full Text] [PDF]




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