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J Thorac Cardiovasc Surg 1997;114:76-83
© 1997 Mosby, Inc.

GENERAL THORACIC SURGERY

AN EXPERIMENTAL MODEL FOR THE PREVENTION OF POSTANASTOMOTIC TRACHEAL STENOSIS

Supported in part by grant 94/0635 from the Fondo de Investigaciones Sanitarias de la Seguridad Social, Ministerio de Sanidad, Madrid, Spain.

Received for publication August 20, 1996; revisions requested Jan. 30, 1997; revisions received Feb. 20, 1997; accepted for publication Feb. 25, 1997. Address for reprints: Jerónimo Gonzálvez-Piñera, Sección de Cirugia Pediátrica, Hospital General de Albacete, C/Hermanos Falcó, s/n°, 02006 Albacete, Spain.

Abstract

Objective: The aim of the current study is to determine the efficiency of an external prosthesis made of expanded polytetrafluoroethylene reinforced with a continuous silicone spiral to prevent postanastomotic stenosis after surgical correction of extensive tracheal defects in rabbits. Methods: Forty-five rabbits were used, divided into three groups of 15 animals each. Group A was the control group. Group B animals underwent resection of six-ring segments of the cervical trachea and primary anastomosis. The procedure used in group C was similar to that used in group B, but the tracheal anastomosis was supported by an external expanded polytetrafluoroethylene prosthesis. Results: Direct anastomosis after resection of six tracheal rings caused anastomotic stenosis in 100% of the animals. We did not observe tracheal stenosis in any rabbit when we applied an expanded polytetrafluoroethylene tube as an external stent for the tracheotracheal suture. Conclusion: We conclude that an external stent can be used to prevent tracheal stenosis resulting from the resection of six cervical tracheal rings in rabbits

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