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J Thorac Cardiovasc Surg 1999;117:54-65
© 1999 Mosby, Inc.
GENERAL THORACIC SURGERY |
From the Division of Thoracic Surgery and the Department of Pathology, Brigham and Women's Hospital; Surgical Services and the Department of Adult Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass; and Hematology-Oncology, University of Massachusetts, Worcester, Mass.
Read at the Seventy-eighth Annual Meeting of The American Association for Thoracic Surgery, Boston, Mass, May 3-6, 1998.
Received for publication May 8, 1998. Revisions requested June 30, 1998. Revisions received Sept 25, 1998. Accepted for publication Sept 29, 1998. Address for reprints: David J. Sugarbaker, MD, Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, MA 02115.
Objectives: Our aim was to identify prognostic variables for long-term postoperative survival in trimodality management of malignant pleural mesothelioma.
Methods: From 1980 to 1997, 183 patients underwent extrapleural pneumonectomy followed by adjuvant chemotherapy and radiotherapy.
Results: Forty-three women and 140 men (age range 31-76 years) had a median follow-up of 13 months. The perioperative mortality rate was 3.8% (7 deaths) and the morbidity, 50%. Survival in the 176 remaining patients was 38% at 2 years and 15% at 5 years (median 19 months). Univariate analysis identified 3 prognostic variables associated with improved survival: epithelial cell type (52% 2-year survival, 21% 5-year survival, 26-month median survival; P = .0001), negative resection margins (44% at 2 years, 25% at 5 years, median 23 months; P = .02), and extrapleural nodes without metastases (42% at 2 years, 17% at 5 years, median 21 months; P = .004). Using the Cox proportional hazards, the relative risk of death was calculated for nonepithelial cell type (OR 3.0, CI 2.0-4.5; P < .0001), positive resection margins (OR 1.7, CI 1.2-2.6; P = .0082), and metastatic extrapleural nodes (OR 2.0, CI 1.3-3.2; P = .0026). Thirty-one patients with 3 positive variables had the best survival (68% 2-year survival, 46% 5-year survival, median 51 months; P = .013). A previously published staging system using these variables stratified survival (P < .05).
Conclusions: (1) Multimodality therapy including extrapleural pneumonectomy is feasible in selected patients with malignant pleural mesotheliomas, (2) pre-resectional evaluation of extrapleural nodes may select patients for radical therapy, (3) microscopic resection margins affect long-term survival, highlighting the need for further investigation of locoregional control, and (4) patients with epithelial, margin-negative, extrapleural node–negative resection had extended survival.
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|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
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|
|
|
|
|
|
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|
|
|
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|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
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|
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|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 P. P. Agarwal, J. M. Seely, F. R. Matzinger, R. M. MacRae, R. A. Peterson, D. E. Maziak, and C. J. Dennie Pleural Mesothelioma: Sensitivity and Incidence of Needle Track Seeding after Image-guided Biopsy versus Surgical Biopsy Radiology, November 1, 2006; 241(2): 589 - 594. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
T. Treasure, C. Tan, L. Lang-Lazdunski, and D. Waller The MARS trial: mesothelioma and radical surgery Interactive CardioVascular and Thoracic Surgery, February 1, 2006; 5(1): 58 - 59. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
D. H. Sterman, A. Recio, A. Vachani, J. Sun, L. Cheung, P. DeLong, K. M. Amin, L. A. Litzky, J. M. Wilson, L. R. Kaiser, et al. Long-term Follow-up of Patients with Malignant Pleural Mesothelioma Receiving High-Dose Adenovirus Herpes Simplex Thymidine Kinase/Ganciclovir Suicide Gene Therapy Clin. Cancer Res., October 15, 2005; 11(20): 7444 - 7453. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Tan and T. Treasure Mesothelioma: time to take stock J R Soc Med, October 1, 2005; 98(10): 455 - 458. [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
P. A. Rascoe, X. Cao, J. C. Daniel, S. D. Miller, and W. R. Smythe Receptor tyrosine kinase and phosphoinositide-3 kinase signaling in malignant mesothelioma J. Thorac. Cardiovasc. Surg., August 1, 2005; 130(2): 393 - 400. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
 |
|
 L. M. Argote-Greene, M. Y. Chang, and D. J. Sugarbaker Extrapleural pneumonectomy for malignant pleural mesothelioma MMCTS, June 28, 2005; 2005(0628): 133. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
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|
 |
|
 S. Neragi-Miandoab, S. P. Gangadharan, and D. J. Sugarbaker Cardiac Sarcoma 14 Years after Treatment for Pleural Mesothelioma N. Engl. J. Med., May 5, 2005; 352(18): 1929 - 1930. [Full Text] [PDF]
|
|
|
|
|
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R. Bueno, J. Reblando, J. Glickman, M. T. Jaklitsch, J. M. Lukanich, and D. J. Sugarbaker Pleural Biopsy: A Reliable Method for Determining the Diagnosis But Not Subtype in Mesothelioma Ann. Thorac. Surg., November 1, 2004; 78(5): 1774 - 1776. [Abstract] [Full Text] [PDF]
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Y. Aelony Need for Further Information on Pemetrexed Study J. Clin. Oncol., October 15, 2004; 22(20): 4234 - 4235. [Full Text] [PDF]
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 M. Pistolesi and J. Rusthoven Malignant Pleural Mesothelioma: Update, Current Management, and Newer Therapeutic Strategies Chest, October 1, 2004; 126(4): 1318 - 1329. [Abstract] [Full Text] [PDF]
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W. Weder, P. Kestenholz, C. Taverna, S. Bodis, D. Lardinois, M. Jerman, and R. A. Stahel Neoadjuvant Chemotherapy Followed by Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma J. Clin. Oncol., September 1, 2004; 22(17): 3451 - 3457. [Abstract] [Full Text] [PDF]
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E. Andreopoulou, P. J. Ross, M. E. R. O'Brien, H. E. R. Ford, K. Priest, T. Eisen, A. Norton, S. Ashley, and I. E. Smith The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma Ann. Onc., September 1, 2004; 15(9): 1406 - 1412. [Abstract] [Full Text] [PDF]
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D. J. Stewart, A. Martin-Ucar, J. E. Pilling, J. G. Edwards, K. J. O'Byrne, and D. A. Waller The effect of extent of local resection on patterns of disease progression in malignant pleural mesothelioma Ann. Thorac. Surg., July 1, 2004; 78(1): 245 - 252. [Abstract] [Full Text] [PDF]
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D. J. Sugarbaker, M. T. Jaklitsch, R. Bueno, W. Richards, J. Lukanich, S. J. Mentzer, Y. Colson, P. Linden, M. Chang, L. Capalbo, et al. Prevention, early detection, and management of complications after 328 consecutive extrapleural pneumonectomies J. Thorac. Cardiovasc. Surg., July 1, 2004; 128(1): 138 - 146. [Abstract] [Full Text] [PDF]
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 H. Kramer, R. M. Pieterman, D.-J. Slebos, W. Timens, W. Vaalburg, G. H. Koeter, and H. J.M. Groen PET for the Evaluation of Pleural Thickening Observed on CT J. Nucl. Med., June 1, 2004; 45(6): 995 - 998. [Abstract] [Full Text] [PDF]
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 M. K. Ozvaran, X. X. Cao, S. D. Miller, B. A. Monia, W. K. Hong, and W. R. Smythe Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma Mol. Cancer Ther., May 1, 2004; 3(5): 545 - 550. [Abstract] [Full Text] [PDF]
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A Baldi, D Santini, F Vasaturo, M Santini, G Vicidomini, M P. Di Marino, V Esposito, A M Groeger, G Liuzzi, B Vincenzi, et al. Prognostic significance of cyclooxygenase-2 (COX-2) and expression of cell cycle inhibitors p21 and p27 in human pleural malignant mesothelioma Thorax, May 1, 2004; 59(5): 428 - 433. [Abstract] [Full Text] [PDF]
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J.E. Pilling, D.J. Stewart, A.E. Martin-Ucar, S. Muller, K.J. O'Byrne, and D.A. Waller The case for routine cervical mediastinoscopy prior to radical surgery for malignant pleural mesothelioma Eur. J. Cardiothorac. Surg., April 1, 2004; 25(4): 497 - 501. [Abstract] [Full Text] [PDF]
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 A. Sharma, P. Fidias, L. A. Hayman, S. L. Loomis, K. H. Taber, and S. L. Aquino Patterns of Lymphadenopathy in Thoracic Malignancies RadioGraphics, March 1, 2004; 24(2): 419 - 434. [Abstract] [Full Text] [PDF]
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Z. J. Wang, G. P. Reddy, M. B. Gotway, C. B. Higgins, D. M. Jablons, M. Ramaswamy, R. A. Hawkins, and W. R. Webb Malignant Pleural Mesothelioma: Evaluation with CT, MR Imaging, and PET RadioGraphics, January 1, 2004; 24(1): 105 - 119. [Abstract] [Full Text] [PDF]
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V H Gerbaudo, S Britz-Cunningham, D J Sugarbaker, and S T Treves Metabolic significance of the pattern, intensity and kinetics of 18F-FDG uptake in malignant pleural mesothelioma Thorax, December 1, 2003; 58(12): 1077 - 1082. [Abstract] [Full Text] [PDF]
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J. G. Edwards, D. E. B. Swinson, J. L. Jones, S. Muller, D. A. Waller, and K. J. O'Byrne Tumor Necrosis Correlates With Angiogenesis and Is a Predictor of Poor Prognosis in Malignant Mesothelioma Chest, November 1, 2003; 124(5): 1916 - 1923. [Abstract] [Full Text] [PDF]
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C Parker and E Neville Lung cancer * 8: Management of malignant mesothelioma Thorax, September 1, 2003; 58(9): 809 - 813. [Full Text] [PDF]
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V. W. Rusch Pemetrexed and Cisplatin for Malignant Pleural Mesothelioma: A New Standard of Care? J. Clin. Oncol., July 15, 2003; 21(14): 2629 - 2630. [Full Text] [PDF]
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R. M. Flores, T. Akhurst, M. Gonen, S. M. Larson, and V. W. Rusch Positron emission tomography defines metastatic disease but not locoregional disease in patients with malignant pleural mesothelioma J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 11 - 15. [Abstract] [Full Text] [PDF]
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J. H. Schouwink, L. Schultze Kool, E. J. Rutgers, F. A. N. Zoetmulder, N. van Zandwijk, M. J. v.d. Vijver, and P. Baas The value of chest computer tomography and cervical mediastinoscopy in the preoperative assessment of patients with malignant pleural mesothelioma Ann. Thorac. Surg., June 1, 2003; 75(6): 1715 - 1718. [Abstract] [Full Text] [PDF]
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G. J. Gordon, R. V. Jensen, L.-L. Hsiao, S. R. Gullans, J. E. Blumenstock, W. G. Richards, M. T. Jaklitsch, D. J. Sugarbaker, and R. Bueno Using Gene Expression Ratios to Predict Outcome Among Patients With Mesothelioma J Natl Cancer Inst, April 16, 2003; 95(8): 598 - 605. [Abstract] [Full Text] [PDF]
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P. G. Phillips, G. Asimakopoulos, and M. O. Maiwand Malignant pleural mesothelioma: outcome of limited surgical management Interactive CardioVascular and Thoracic Surgery, March 1, 2003; 2(1): 30 - 34. [Abstract] [Full Text] [PDF]
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Y. Aelony Missing data from mesothelioma study J. Thorac. Cardiovasc. Surg., February 1, 2003; 125(2): 442 - 443. [Full Text] [PDF]
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H. I. Pass Pleural mesothelioma in 2002: Going somewhere very slowly J. Thorac. Cardiovasc. Surg., December 1, 2002; 124(6): 1074 - 1077. [Full Text]
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T. T. Lee, D. L. Everett, H.-K. G. Shu, T. M. Jahan, M. Roach III, J. L. Speight, R. B. Cameron, T. L. Phillips, A. Chan, and D. M. Jablons Radical pleurectomy/decortication and intraoperative radiotherapy followed by conformal radiation with or without chemotherapy for malignant pleural mesothelioma J. Thorac. Cardiovasc. Surg., December 1, 2002; 124(6): 1183 - 1189. [Abstract] [Full Text]
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P. Bonnette, G. B. Heckly, S. Villette, A. Fragola, J. H. Schouwink, and P. Bass Intraoperative Photodynamic Therapy After Pleuropneumonectomy for Malignant Pleural Mesothelioma Chest, November 1, 2002; 122(5): 1866 - 1867. [Full Text] [PDF]
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 P. A. Janne, M. L. Taffaro, R. Salgia, and B. E. Johnson Inhibition of Epidermal Growth Factor Receptor Signaling in Malignant Pleural Mesothelioma Cancer Res., September 15, 2002; 62(18): 5242 - 5247. [Abstract] [Full Text] [PDF]
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V. H. Gerbaudo, D. J. Sugarbaker, S. Britz-Cunningham, M. F. Di Carli, C. Mauceri, and S. T. Treves Assessment of Malignant Pleural Mesothelioma with 18F-FDG Dual-Head Gamma-Camera Coincidence Imaging: Comparison with Histopathology J. Nucl. Med., September 1, 2002; 43(9): 1144 - 1149. [Abstract] [Full Text] [PDF]
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W. R. Smythe, I. Mohuiddin, M. Ozveran, and X. X. Cao Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product J. Thorac. Cardiovasc. Surg., June 1, 2002; 123(6): 1191 - 1198. [Abstract] [Full Text] [PDF]
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 G. J. Gordon, K. Appasani, J. P. Parcells, N. K. Mukhopadhyay, M. T. Jaklitsch, W. G. Richards, D. J. Sugarbaker, and R. Bueno Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma Carcinogenesis, June 1, 2002; 23(6): 1017 - 1024. [Abstract] [Full Text] [PDF]
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J. G. Edwards, S. P. Faux, S. M. Plummer, K. R. Abrams, R. A. Walker, D. A. Waller, and K. J. O'Byrne Cyclooxygenase-2 Expression Is a Novel Prognostic Factor in Malignant Mesothelioma Clin. Cancer Res., June 1, 2002; 8(6): 1857 - 1862. [Abstract] [Full Text] [PDF]
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 X. X. Cao, I. Mohuiddin, F. Ece, D. J. McConkey, and W. R. Smythe Histone Deacetylase Inhibitor Downregulation of bcl-xl Gene Expression Leads to Apoptotic Cell Death in Mesothelioma Am. J. Respir. Cell Mol. Biol., November 1, 2001; 25(5): 562 - 568. [Abstract] [Full Text] [PDF]
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