| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Thorac Cardiovasc Surg 2000;119:440-448
© 2000 Mosby, Inc.
GENERAL THORACIC SURGERY |
From the Departments of Surgery and Health Studies, The University of Chicago, Chicago, Ill.
Address for reprints: Mark K. Ferguson, MD, Section of Cardiac and Thoracic Surgery, The University of Chicago, 5841 S Maryland Ave, MC5035, Chicago, IL 60637 (E-mail: mferguso{at}surgery.bsd.uchicago.edu ).
Objective: The increased operative mortality associated with pneumonectomy has stimulated the use of lung-sparing operations such as sleeve lobectomy. Whether pneumonectomy adversely affects long-term outcome after lung resection is unknown.
Methods: We reviewed the cases of patients who underwent lobectomy/bilobectomy or pneumonectomy because of non–small cell lung cancer between January 1980 and June 1998. Survival curves were compared by the log-rank test. Covariates were determined for operative mortality and survival using logistic regression analysis and Cox proportional hazards estimation, respectively.
Results: There were 259 men and 183 women who underwent lobectomy/bilobectomy (340) or pneumonectomy (102). Operative mortality was 36 (8.1%) patients overall, 24 (7.0%) for lobectomy/bilobectomy and 12 (12%) for pneumonectomy. Mean follow-up was 41 months (range 0-222 months). Median survival was worse for pneumonectomy (stage II: 17.9 vs 36.3 months, log-rank P = .05; stage III: 11.7 vs 21.3 months, log-rank P = .07). However, important covariates for survival were age, primary tumor status, regional nodal status, and forced expiratory volume in 1 second. After adjusting for these covariates, survival did not differ significantly between the types of operations (hazard ratio for pneumonectomy 1.21; 95% CI 0.88-1.68).
Conclusions: We did not detect a significant long-term adverse influence of pneumonectomy on survival after adjusting for other prognostic factors, but randomized clinical trials would be needed to definitively address this issue.
This article has been cited by other articles:
|
|
 |
|
  C. Simon, N. Moreno, R. Penalver, G. Gonzalez, E. Alvarez-Fernandez, F. Gonzalez-Aragoneses, and Bronchogenic Carcinoma Cooperative Group of the Sp The Side of Pneumonectomy Influences Long-Term Survival in Stage I and II Non-Small Cell Lung Cancer Ann. Thorac. Surg., September 1, 2007; 84(3): 952 - 958. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Ma, A. Dong, J. Fan, and H. Cheng Does sleeve lobectomy concomitant with or without pulmonary artery reconstruction (double sleeve) have favorable results for non-small cell lung cancer compared with pneumonectomy? A meta-analysis Eur. J. Cardiothorac. Surg., July 1, 2007; 32(1): 20 - 28. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. Kim, J. G. Lee, C. Y. Lee, I.-k. Park, and K. Y. Chung Long-term Survival Following Pneumonectomy for Non-Small Cell Lung Cancer: Clinical Implications for Follow-up Care Chest, July 1, 2007; 132(1): 178 - 184. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Yildizeli, E. Fadel, S. Mussot, D. Fabre, O. Chataigner, and P. G. Dartevelle Morbidity, mortality, and long-term survival after sleeve lobectomy for non-small cell lung cancer Eur. J. Cardiothorac. Surg., January 1, 2007; 31(1): 95 - 102. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Lemaitre, Z. Mansour, E. A. Kochetkova, C. Koriche, X. Ducrocq, J.-M. Wihlm, E. Quoix, and G. Massard Bronchoplastic lobectomy: do early results depend on the underlying pathology? A comparison between typical carcinoids and primary lung cancer. Eur. J. Cardiothorac. Surg., July 1, 2006; 30(1): 168 - 171. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-i. Takeda, H. Maeda, M. Koma, Y. Matsubara, N. Sawabata, M. Inoue, T. Tokunaga, and M. Ohta Comparison of surgical results after pneumonectomy and sleeve lobectomy for non-small cell lung cancer.: Trends over time and 20-year institutional experience Eur. J. Cardiothorac. Surg., March 1, 2006; 29(3): 276 - 280. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-F. Regnard, C. Perrotin, R. Giovannetti, O. Schussler, A. Petino, L. Spaggiari, M. Alifano, and P. Magdeleinat Resection for Tumors With Carinal Involvement: Technical Aspects, Results, and Prognostic Factors Ann. Thorac. Surg., November 1, 2005; 80(5): 1841 - 1846. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. T. Kim, C. H. Kang, S. W. Sung, and J. H. Kim Local Control of Disease Related to Lymph Node Involvement in Non-Small Cell Lung Cancer After Sleeve Lobectomy Compared With Pneumonectomy Ann. Thorac. Surg., April 1, 2005; 79(4): 1153 - 1161. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Aguilo and J. Minguella Short- and Long-Term Mortality After Pulmonary Resection Ann. Thorac. Surg., January 1, 2005; 79(1): 385 - 386. [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. Patel, P. B. Bach, and M. G. Kris Lung Cancer in US Women: A Contemporary Epidemic JAMA, April 14, 2004; 291(14): 1763 - 1768. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. K. Ferguson and A. G. Lehman Sleeve lobectomy or pneumonectomy: optimal management strategy using decision analysis techniques Ann. Thorac. Surg., December 1, 2003; 76(6): 1782 - 1788. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Alexiou, D. Beggs, P. Onyeaka, K. Kotidis, S. Ghosh, L. Beggs, D. N. Hopkinson, J. P. Duffy, W. E. Morgan, and G. Rocco Pneumonectomy for Stage I (T1N0 and T2N0) nonsmall cell lung cancer has potent, adverse impact on survival Ann. Thorac. Surg., October 1, 2003; 76(4): 1023 - 1028. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Varela, M. F. Jimenez, N. Novoa, and P. Macri Discordance between predicted postoperative forced expiratory volumes in one second (ppoFEV1) calculated before and after resection of bronchogenic carcinoma Interactive CardioVascular and Thoracic Surgery, June 1, 2003; 2(2): 138 - 142. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. K. Ferguson and A. E. Durkin A comparison of three scoring systems for predicting complications after major lung resection Eur. J. Cardiothorac. Surg., January 1, 2003; 23(1): 35 - 42. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Fadel, B. Yildizeli, A. R. Chapelier, I. Dicenta, S. Mussot, and P. G. Dartevelle Sleeve lobectomy for bronchogenic cancers: factors affecting survival Ann. Thorac. Surg., September 1, 2002; 74(3): 851 - 859. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Terzi, A. Lonardoni, G. Falezza, G. Furlan, P. Scanagatta, F. Pasini, and F. Calabro Sleeve lobectomy for non-small cell lung cancer and carcinoids: results in 160 cases Eur. J. Cardiothorac. Surg., May 1, 2002; 21(5): 888 - 893. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Martin, R. J. Ginsberg, E. S. Venkatraman, M. S. Bains, R. J. Downey, R. J. Korst, M. G. Kris, and V. W. Rusch Long-Term Results of Combined-Modality Therapy in Resectable Non-Small-Cell Lung Cancer J. Clin. Oncol., April 15, 2002; 20(8): 1989 - 1995. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Thomas, C. Doddoli, X. Thirion, O. Ghez, M.-J. Payan-Defais, R. Giudicelli, and P. Fuentes Stage I non-small cell lung cancer: a pragmatic approach to prognosis after complete resection Ann. Thorac. Surg., April 1, 2002; 73(4): 1065 - 1070. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Handy Jr, A. I. Child, G. L. Grunkemeier, P. Fowler, J. W. Asaph, E. C. Douville, A. C. Tsen, and G. Y. Ott Hospital readmission after pulmonary resection: prevalence, patterns, and predisposing characteristics Ann. Thorac. Surg., December 1, 2001; 72(6): 1855 - 1860. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Machtay, J. H. Lee, J. B. Shrager, L. R. Kaiser, and E. Glatstein Risk of Death From Intercurrent Disease Is Not Excessively Increased by Modern Postoperative Radiotherapy for High-Risk Resected Non-Small-Cell Lung Carcinoma J. Clin. Oncol., October 1, 2001; 19(19): 3912 - 3917. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
