| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Thorac Cardiovasc Surg 2000;119:525-533
© 2000 Mosby, Inc.
SURGERY FOR CONGENITAL HEART DISEASE |
From the Cardiothoracic Unit,a Great Ormond Street Hospital for Children NHS Trust, London; and the Departments of Cardiac Surgery,b Anaesthesia,c and Paediatrics,d Royal Brompton and Harefield NHS Trust, London, United Kingdom.
Supported by the British Heart Foundation.
Address for reprints: Professor Andrew N. Redington, Professor of Cardiology, Cardiothoracic Unit, Great Ormond Street Hospital for Children NHS Trust, Great Ormond St, London WC1N 3JH (E-mail: reding{at}ibm.net ).
Objective: We sought to assess oxygen consumption and its determinants in children shortly after undergoing cardiopulmonary bypass operations.
Methods: Twenty children, aged 2 months to 15 years (median, 3.75 years), undergoing hypothermic cardiopulmonary bypass operations were studied during the first 4 hours after arrival in the intensive care unit. Central and peripheral temperatures were monitored. Oxygen consumption was continuously measured by using respiratory mass spectrometry. Oxygen delivery was calculated from oxygen consumption and arterial and mixed venous oxygen contents, which were sampled every 30 minutes. Oxygen extraction was derived by the ratio of oxygen consumption and oxygen delivery. Arterial blood lactate levels were measured every 30 minutes.
Results: There was a correlation between oxygen consumption and age in patients older than 3 months (r = –0.76). Mean oxygen consumption increased by 14.7% during the study. The increase in oxygen consumption was correlated with the increase in central temperature (r = 0.73). Nine patients had an arterial lactate level above 2 mmol/L on arrival. There were no significant differences in oxygen consumption, oxygen delivery, and oxygen extraction between the group with lactate levels between 2 and 3 mmol/L and the groups with normal lactate levels both on arrival and at 2 hours. One patient with a peak lactate level of 6.8 mmol/L had initially low oxygen delivery (241.3 mL · min–1 · m–2).
Conclusions: During the early hours after a pediatric cardiac operation, the increase in oxygen consumption is mainly attributed to the increase in central temperature. Oxygen consumption is negatively related to age. Mild lactatemia is common and does not appear to reflect oxygen delivery or oxygen consumption or a more complicated recovery.
This article has been cited by other articles:
|
|
 |
|
  J. Li, G. Zhang, H. Holtby, S. Cai, M. Walsh, C. A. Caldarone, and G. S. Van Arsdell Significant correlation of comprehensive Aristotle score with total cardiac output during the early postoperative period after the Norwood procedure J. Thorac. Cardiovasc. Surg., July 1, 2008; 136(1): 123 - 128. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Li, G. Zhang, L. Benson, H. Holtby, S. Cai, T. Humpl, G. S. Van Arsdell, A. N. Redington, and C. A. Caldarone Comparison of the Profiles of Postoperative Systemic Hemodynamics and Oxygen Transport in Neonates After the Hybrid or the Norwood Procedure: A Pilot Study Circulation, September 11, 2007; 116(11_suppl): I-179 - I-187. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Li, G. Zhang, B. W. McCrindle, H. Holtby, T. Humpl, S. Cai, C. A. Caldarone, A. N. Redington, and G. S. Van Arsdell Profiles of hemodynamics and oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure J. Thorac. Cardiovasc. Surg., February 1, 2007; 133(2): 441 - 448. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Li, G. Zhang, H. Holtby, T. Humpl, C. A. Caldarone, G. S. Van Arsdell, and A. N. Redington Adverse Effects of Dopamine on Systemic Hemodynamic Status and Oxygen Transport in Neonates After the Norwood Procedure J. Am. Coll. Cardiol., November 7, 2006; 48(9): 1859 - 1864. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J Li, G S Van Arsdell, G Zhang, S Cai, T Humpl, C A Caldarone, H Holtby, and A N Redington Assessment of the relationship between cerebral and splanchnic oxygen saturations measured by near-infrared spectroscopy and direct measurements of systemic haemodynamic variables and oxygen transport after the Norwood procedure Heart, November 1, 2006; 92(11): 1678 - 1685. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R K Kharbanda, J Li, I E Konstantinov, M M H Cheung, P A White, H Frndova, J Stokoe, P Cox, M Vogel, G Van Arsdell, et al. Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study Heart, October 1, 2006; 92(10): 1506 - 1511. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Li, G. Zhang, H. M. Holtby, B. W. McCrindle, S. Cai, T. Humpl, C. A. Caldarone, W. G. Williams, A. N. Redington, and G. S. Van Arsdell Inclusion of oxygen consumption improves the accuracy of arterial and venous oxygen saturation interpretation after the Norwood procedure J. Thorac. Cardiovasc. Surg., May 1, 2006; 131(5): 1099 - 1107. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Intracardiac temperature monitoring in infants after cardiac surgery. J. Thorac. Cardiovasc. Surg., March 1, 2006; 131(3): 614 - 620.
|
|
|
|
|
|
U. Fakler and J. Hess Reply to the Editor J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 252 - 252. [Full Text] [PDF]
|
|
|
|
|
|
J. Li, I. E. Konstantinov, G. S. Van Arsdell, and A. N. Redington Assumed oxygen consumption in the determination of cardiac output in children after cardiac surgery J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 251 - 251. [Full Text] [PDF]
|
|
|
|
 |
|
 J. Li, A. Hoschtitzky, M. L. Allen, M. J. Elliott, and A. N. Redington An Analysis of Oxygen Consumption and Oxygen Delivery in Euthermic Infants After Cardiopulmonary Bypass With Modified Ultrafiltration Ann. Thorac. Surg., October 1, 2004; 78(4): 1389 - 1396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Li, J. Stokoe, I. E. Konstantinov, D. Edgell, M. M. H. Cheung, R. K. Kharbanda, and A. N. Redington Continuous measurement of oxygen consumption during cardiopulmonary bypass: description of the method and in vivo observations Ann. Thorac. Surg., May 1, 2004; 77(5): 1671 - 1677. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Li, E. Stenbog, A. Bush, T. Grofte, A. N. Redington, and D. J. Penny Insulin-like growth factor 1 improves the relationship between systemic oxygen consumption and delivery in piglets after cardiopulmonary bypass J. Thorac. Cardiovasc. Surg., May 1, 2004; 127(5): 1436 - 1441. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Ootaki, M. Yamaguchi, N. Yoshimura, S. Oka, M. Yoshida, and T. Hasegawa Efficacy of a criterion-driven transfusion protocol in patients having pediatric cardiac surgery J. Thorac. Cardiovasc. Surg., April 1, 2004; 127(4): 953 - 958. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. A. Schroeder, J. M. Pearl, S. M. Schwartz, T. P. Shanley, P. B. Manning, and D. P. Nelson Combined Steroid Treatment for Congenital Heart Surgery Improves Oxygen Delivery and Reduces Postbypass Inflammatory Mediator Expression Circulation, June 10, 2003; 107(22): 2823 - 2828. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Schulze-Neick, J. Li, D. J. Penny, and A. N. Redington Pulmonary vascular resistance after cardiopulmonary bypass in infants: Effect on postoperative recovery J. Thorac. Cardiovasc. Surg., June 1, 2001; 121(6): 1033 - 1039. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T.-A. Miyamoto and K.-J. Miyamoto Alternate explanation for the increasing oxygen consumption and lactatemia after surgery with hypothermic cardiopulmonary bypass J. Thorac. Cardiovasc. Surg., April 1, 2001; 121(4): 816 - 817. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
