HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Francisco J. Puga Joseph A. Dearani Gordon K. Danielson Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by El-Najdawi, E. K. Articles by Danielson, G. K. Search for Related Content PubMed PubMed Citation Articles by El-Najdawi, E. K. Articles by Danielson, G. K.

J Thorac Cardiovasc Surg 2000;119:880-889
© 2000 The American Association for Thoracic Surgery

Surgery For Congenital Heart Disease

Operation for partial atrioventricular septal defect: a forty-year review

From the Section of Pediatric Cardiology,^a the Division of Thoracic and Cardiovascular Surgery,^b and the Section of Biostatistics,^c Mayo Clinic and Mayo Foundation, Rochester, Minn.

Address for reprints: David J. Driscoll, MD, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (E-mail: driscoll.david @mayo.edu ).

Background: We describe the long-term outcome of repair of partial atrioventricular septal defect by determining the rates of survival, reoperation, and occurrence of left atrioventricular valve regurgitation, left atrioventricular valve stenosis, left ventricular outflow tract obstruction, and arrhythmia.
Methods: We studied 334 patients who underwent repair of partial atrioventricular septal defect before 1995.
Results: The 30-day and 5-, 10-, 20-, and 40-year survival were 98%, 94%, 93%, 87%, and 76%, respectively. Closure of the left atrioventricular valve cleft (P = .03) and age less than 20 years at operation (P < .001) were associated with better survival. Reoperation was performed for 38 patients (11%). Repair of residual/recurrent left atrioventricular valve regurgitation or stenosis was the most common reason for reoperation. Left ventricular outflow tract obstruction occurred in 36 patients, and 7 patients underwent reoperation to relieve this obstruction. Supraventricular arrhythmias were observed in 58 patients (16%) after the operation. Supraventricular arrhythmias increased with increasing age at primary operation (P = .001). Complete atrioventricular block occurred in 9 patients (3%). Permanent pacemakers were implanted in 11 patients.
Conclusions: Long-term survival after repair of partial atrioventricular septal defect is good. It is important to close the cleft in the left atrioventricular valve. Reoperation for persistent or recurrent left atrioventricular valve malfunction and relief of left ventricular outflow tract obstruction is necessary in approximately 11% of patients.

This article has been cited by other articles:

				G. J.F. Hoohenkerk, A. C.G. Wenink, P. H. Schoof, D. R. Koolbergen, E. F. Bruggemans, M. Rijlaarsdam, and M. G. Hazekamp Results of surgical repair of atrioventricular septal defect with double-orifice left atrioventricular valve J. Thorac. Cardiovasc. Surg., November 1, 2009; 138(5): 1167 - 1171. [Abstract] [Full Text] [PDF]

				J. H. Shuhaiber, S. Y. Ho, M. Rigby, and B. Sethia Current options and outcomes for the management of atrioventricular septal defect Eur. J. Cardiothorac. Surg., May 1, 2009; 35(5): 891 - 900. [Abstract] [Full Text] [PDF]

				U. K. Chowdhury, B. Airan, A. Malhotra, A. K. Bisoi, M. Kalaivani, R. M. Govindappa, and P. Venugopal Specific issues after surgical repair of partial atrioventricular septal defect: actuarial survival, freedom from reoperation, fate of the left atrioventricular valve, prevalence of left ventricular outflow tract obstruction, and other events. J. Thorac. Cardiovasc. Surg., March 1, 2009; 137(3): 548 - 555.e2. [Abstract] [Full Text] [PDF]

				E. Bedard, D. F. Shore, and M. A. Gatzoulis Adult congenital heart disease: a 2008 overview Br. Med. Bull., March 1, 2008; 85(1): 151 - 180. [Abstract] [Full Text] [PDF]

				H. Laks, D. Marelli, M. Plunkett, and J. Myers Adult Congenital Heart Disease Card. Surg. Adult, January 1, 2008; 3(2008): 1431 - 1464. [Full Text]

				K. F. Welke, C. D. Morris, E. King, C. Komanapalli, M. D. Reller, and R. M. Ungerleider Population-Based Perspective of Long-Term Outcomes After Surgical Repair of Partial Atrioventricular Septal Defect Ann. Thorac. Surg., August 1, 2007; 84(2): 624 - 629. [Abstract] [Full Text] [PDF]

				B. Craig Atrioventricular septal defect: from fetus to adult Heart, December 1, 2006; 92(12): 1879 - 1885. [Full Text] [PDF]

				Y.-Q. Lai, Y. Luo, C. Zhang, and Z.-G. Zhang Utilization of Double-Orifice Valve Plasty in Correction of Atrioventricular Septal Defect Ann. Thorac. Surg., April 1, 2006; 81(4): 1450 - 1454. [Abstract] [Full Text] [PDF]

				S. Aubert, R. Henaine, O. Raisky, N. Chavanis, J. Robin, R. Ecochard, and J. Ninet Atypical forms of isolated partial atrioventricular septal defect increase the risk of initial valve replacement and reoperation Eur. J. Cardiothorac. Surg., August 1, 2005; 28(2): 223 - 228. [Abstract] [Full Text] [PDF]

				C. Barrea, S. Levasseur, K. Roman, M. Nii, J. G. Coles, W. G. Williams, and J. F. Smallhorn Three-dimensional echocardiography improves the understanding of left atrioventricular valve morphology and function in atrioventricular septal defects undergoing patch augmentation J. Thorac. Cardiovasc. Surg., April 1, 2005; 129(4): 746 - 753. [Abstract] [Full Text] [PDF]

				A. A.A. Al-Hay, C. R. Lincoln, D. F. Shore, and E. A. Shinebourne The left atrioventricular valve in partial atrioventricular septal defect: management strategy and surgical outcome Eur. J. Cardiothorac. Surg., October 1, 2004; 26(4): 754 - 761. [Abstract] [Full Text] [PDF]

				A. Boening, J. Scheewe, K. Heine, J. Hedderich, D. Regensburger, H.-H. Kramer, and J. Cremer Long-term results after surgical correction of atrioventricular septal defects Eur. J. Cardiothorac. Surg., August 1, 2002; 22(2): 167 - 173. [Abstract] [Full Text] [PDF]

				T. Nitta, H. Yamauchi, N. Ohkubo, Y. Ishii, S. Tanaka, M. Hayashi, Y. Kobayashi, and T. Takano Modification of the radial procedure in a patient with partial atrioventricular septal defect Ann. Thorac. Surg., February 1, 2002; 73(2): 661 - 663. [Abstract] [Full Text] [PDF]

				T. Nakano, H. Kado, Y.-i. Shiokawa, and K. Fukae Surgical results of double-orifice left atrioventricular valve associated with atrioventricular septal defects Ann. Thorac. Surg., January 1, 2002; 73(1): 69 - 75. [Abstract] [Full Text] [PDF]

				R. Lange, C. Schreiber, T. Gunther, M. Wottke, F. Haas, F. Meisner, J. Hess, and K. Holper Results of biventricular repair of congenital cardiac malformations: definitive corrective surgery? Eur. J. Cardiothorac. Surg., December 1, 2001; 20(6): 1207 - 1213. [Abstract] [Full Text] [PDF]

				M. Chikada, A. Sekiguchi, T. Miyamoto, M. Matsuzaki, R. Ishida, and A. Ishizawa Direct closure of ostium primum defect in the repair of atrioventricular septal defect Ann. Thorac. Surg., August 1, 2001; 72(2): 430 - 432. [Abstract] [Full Text] [PDF]

				B. Marino, S. Anaclerio, R. Di Donato;, R.-K. R. Chang, and T. S. Klitzner Age at Operation for Children With Atrioventricular Canal Pediatrics, July 1, 2001; 108(1): 217 - 217. [Full Text]

				R. Formigari, G. Gargiulo, and F. M. Picchio Operation for partial atrioventricular septal defect: A forty-year review J. Thorac. Cardiovasc. Surg., February 1, 2001; 121(2): 398 - 399. [Full Text] [PDF]