JTCS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Choudhary, S. K.
Right arrow Articles by Kumar, A. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Choudhary, S. K.
Right arrow Articles by Kumar, A. S.

J Thorac Cardiovasc Surg 2000;120:148-155
© 2000 The American Association for Thoracic Surgery


SURGERY FOR ACQUIRED CARDIOVASCULAR DISEASE

Pulmonary homograftShould it be used in the aortic position?

Shiv Kumar Choudhary, MCh, Anita Saxena, DM, Bharat Dubey, MS, A. Sampath Kumar, MCh

From Cardiothoracic Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Address for reprints: A. Sampath Kumar, MCh, Professor, Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110029, India (E-mail: askumar{at}medinst.ernet.in ).

Objective: Retrospective analysis was performed to determine the suitability of pulmonary homograft as an aortic valve substitute.
Methods: From January 1994 through June 1999, 147 patients (mean age, 32.2 ± 17.3 years) underwent aortic valve replacement with either an aortic homograft (group 1: n = 103, 25 fresh antibiotic preserved and 78 cryopreserved) or a pulmonary homograft (group 2: n = 44, 11 antibiotic preserved and 33 cryopreserved). In group 1 a scalloped subcoronary technique was used in 64 patients, and a root replacement technique was used in 39 patients. In group 2 the scalloped subcoronary technique was used in 34 patients, and the root replacement technique was used in 10 patients.
Results: There were 131 operative survivors (group 1 = 91; group 2 = 40). Follow-up ranged from 2 to 62 months. In group 1 none of the patients had significant aortic regurgitation during the hospital stay. Three patients (all having undergone the scalloped subcoronary technique) had moderate aortic regurgitation after 6 to 32 months. In group 2, 10 patients (9 having undergone the scalloped subcoronary technique and 1 having undergone the root replacement technique) developed significant regurgitation: 2 intraoperatively, 5 in the early postoperative period before discharge from the hospital, and 3 during late follow-up 6 to 12 months postoperatively. Among the various risk factors analyzed for overall homograft failure, use of a pulmonary homograft was the single independent predictor of valve failure (odds ratio, 8.6; 95% confidence interval, 1.9-39; P = .006).
Conclusion: Pulmonary homograft, when inserted by means of a scalloped subcoronary technique, is not a suitable aortic valve substitute.




This article has been cited by other articles:


Home page
Ann. Thorac. Surg.Home page
S. Talwar, R. Mohapatra, A. Saxena, R. Singh, and A. S. Kumar
Aortic Homograft: A Suitable Substitute for Aortic Valve Replacement
Ann. Thorac. Surg., September 1, 2005; 80(3): 832 - 838.
[Abstract] [Full Text] [PDF]


Home page
Eur J Cardiothorac SurgHome page
D. R. Koolbergen, M. G. Hazekamp, E. de Heer, F. van Hoorn, H. A. Huysmans, J. A. Bruijn, and R. A. E. Dion
Structural degeneration of pulmonary homografts used as aortic valve substitute underlines early graft failure
Eur J Cardiothorac Surg, November 1, 2002; 22(5): 802 - 807.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2000 by The American Association for Thoracic Surgery.