JTCS Click here to go to SJM website.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Karunanithi, M. K.
Right arrow Articles by Feneley, M. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Karunanithi, M. K.
Right arrow Articles by Feneley, M. P.

J Thorac Cardiovasc Surg 2000;120:302-312
© 2000 The American Association for Thoracic Surgery

Surgery for acquired cardiovascular disease

Limitations of unidimensional indexes of right ventricular contractile function in conscious dogs

Mohanraj K. Karunanithi, BE, MBiomedE, Michael P. Feneley, MD, FRACP, FACC

From The Victor Chang Cardiac Research Institute and Cardiology Department, St Vincent’s Hospital, Darlinghurst, New South Wales, Australia.

Address for reprints: Michael P. Feneley, MD, FRACP, FACC, Cardiology Department, St Vincent’s Hospital, Darlinghurst, NSW 2010, Australia (E-mail: M.Karunanithi{at}unsw.edu.au ).

Objective: Our goal was to examine the validity of unidimensional indexes of right ventricular contractile performance in vivo.
Methods: Unidimensional indexes and global measurements of right ventricular volume and contractile performance were compared in 6 conscious dogs. Vena caval occlusions were performed before (control) and during pulmonary arterial or aortic constriction.
Results: Moderately strong relationships were demonstrated between right ventricular septal–free wall indexes and global measurements of right ventricular end-diastolic and end-systolic volumes, stroke volume, stroke work, and the slope of the preload recruitable stroke work relationship, respectively, under control conditions (mean r 2 range 0.69-0.94). These relationships were shifted significantly, however, by increased right ventricular afterload. Increased left ventricular afterload significantly shifted the relationships between right ventricular septal–free wall dimensions and end-diastolic and end-systolic volumes. Relationships between the corresponding regional right ventricular free wall segmental indexes and global measurements under control conditions were weaker (mean r 2 range 0.12-0.65) and were significantly more sensitive to distortion by both increased right and left ventricular afterload, the effects of which were generally in opposite directions. These observations are consistent with significant ventricular interactive effects on the relationship between single right ventricular dimensions and right ventricular volume.
Conclusion: Unidimensional right ventricular measurements are not reliable surrogates for right ventricular volume when assessing right ventricular contractile performance in the intact heart.




This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
H. A. Leather, R. Ama', C. Missant, S. Rex, F. E. Rademakers, and P. F. Wouters
Longitudinal but not circumferential deformation reflects global contractile function in the right ventricle with open pericardium
Am J Physiol Heart Circ Physiol, June 1, 2006; 290(6): H2369 - H2375.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2000 by The American Association for Thoracic Surgery.