JTCS Speed Up Your Browser
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Patrick M. McCarthy
Eugene H. Blackstone
James B. Young
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Franco-Cereceda, A.
Right arrow Articles by Starling, R. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Franco-Cereceda, A.
Right arrow Articles by Starling, R. C.
Related Collections
Right arrow Cardiac - other
Right arrow Congestive Heart Failure
Right arrowRelated Article

J Thorac Cardiovasc Surg 2001;121:879-893
© 2001 The American Association for Thoracic Surgery

Cardiothoracic Transplantation

Partial left ventriculectomy for dilated cardiomyopathy: Is this an alternative to transplantation?

Anders Franco-Cereceda, MD, PhD, Patrick M. McCarthy, MD, Eugene H. Blackstone, MD, Katherine J. Hoercher, RN, Jennifer A. White, MS, James B. Young, MD, Randall C. Starling, MD

From the Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio.

Received for publication May 3, 2000. Revisions requested July 11, 2000; revisions received Nov 21, 2000. Accepted for publication Dec 1, 2000. Objective: To determine the late effectiveness of partial left ventriculectomy and risk factors for failure.
Methods: Between May 1996 and December 1998, partial left ventriculectomy and concomitant mitral valve surgery were performed in 62 patients (95% transplant candidates) with a mean age of 54 years (range 17-72 years). All patients were in New York Heart Association functional class III (38%) or IV (62%) because of idiopathic dilated cardiomyopathy (59 patients) or ischemic, valvular, or familial cardiomyopathy (1 patient each). Outcomes considered for multivariable analysis included implantation of left ventricular assist device, return to class IV heart failure, relisting for transplantation, and death.
Results: Partial left ventriculectomy reduced the left ventricular end-diastolic diameter immediately preoperatively to immediately postoperatively (from 8.4 ± 1.1 cm to 5.92 ± 0.8 cm; P = .01), reduced the left ventricular end-diastolic volume index (from 133 ± 48.6 mL to 64.1 ± 26 mL; P < .0001), and increased the left ventricular ejection fraction (from 16 ± 7.6 to 31.5 ± 10.9; P < .0001). Survival was 80% and 60% at 1 and 3 years after surgery and freedom from failure was 49% and 26%, respectively. Increased systolic pulmonary artery pressure, decreased maximum exercise oxygen consumption, and increased left atrial pressure were associated with failure and/or death. The degree of preoperative mitral regurgitation did not correlate with clinical outcome.
Conclusions: Early and late failures preclude the widespread use of partial left ventriculectomy. However, in view of its sometimes beneficial effect, use in situations that do not allow for transplantation or as a biologic bridge to transplantation may be appropriate.


Related Article

A bypass for the Institutional Review Board: Reflections on the Cleveland Clinic study of the Batista operation
Martin F. McKneally
J. Thorac. Cardiovasc. Surg. 2001 121: 837-839. [Extract] [Full Text] [PDF]



This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
A. S. Rubino, F. Onorati, G. Santarpino, E. Pasceri, G. Santarpia, L. Cristodoro, G. F. Serraino, and A. Renzulli
Neurohormonal and echocardiographic results after CorCap and mitral annuloplasty for dilated cardiomyopathy.
Ann. Thorac. Surg., September 1, 2009; 88(3): 719 - 725.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
M. Hori and K. Nishida
Oxidative stress and left ventricular remodelling after myocardial infarction
Cardiovasc Res, February 15, 2009; 81(3): 457 - 464.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
F. Nicolini and T. Gherli
Alternatives to transplantation in the surgical therapy for heart failure
Eur. J. Cardiothorac. Surg., February 1, 2009; 35(2): 214 - 228.
[Abstract] [Full Text] [PDF]

Home page
 ESC Textbook of Cardiovascular MedicineHome page
O. M. Hess, W. McKenna, and H.-P. Schultheiss
CHAPTER 18 Myocardial Disease
ESC Textbook of Cardiovascular Medicine, January 1, 2009; 2(1): med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
H. Suma, H. Tanabe, T. Uejima, S. Suzuki, T. Horii, and T. Isomura
Selected ventriculoplasty for idiopathic dilated cardiomyopathy with advanced congestive heart failure: midterm results and risk analysis
Eur. J. Cardiothorac. Surg., December 1, 2007; 32(6): 912 - 916.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
H. Suma, T. Isomura, T. Horii, and F. Nomura
Septal anterior ventricular exclusion procedure for idiopathic dilated cardiomyopathy.
Ann. Thorac. Surg., October 1, 2006; 82(4): 1344 - 1348.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. Burkhoff and A. S. Wechsler
Surgical ventricular remodeling: A balancing act on systolic and diastolic properties.
J. Thorac. Cardiovasc. Surg., September 1, 2006; 132(3): 459 - 463.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. Iino, H. Ohashi, Y. Tsutsumi, T. Kawai, H. Fujii, and M. Ohnaka
Biventricular Pacing 18 Months After Batista Operation
Ann. Thorac. Surg., June 1, 2006; 81(6): 2302 - 2304.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
H. Suma, T. Horii, T. Isomura, G. Buckberg, and the RESTORE Group
A new concept of ventricular restoration for nonischemic dilated cardiomyopathy
Eur. J. Cardiothorac. Surg., April 1, 2006; 29(Suppl_1): S207 - S212.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
F. Bredin and A. Franco-Cereceda
Reversed remodelling in dilated cardiomyopathy by passive containment surgery is associated with decreased circulating levels of endothelin-1
Eur. J. Cardiothorac. Surg., March 1, 2006; 29(3): 299 - 303.
[Abstract] [Full Text] [PDF]

Home page
 Asian Cardiovasc. Thorac. Ann.Home page
V. Chekanov, A. Dumcius, and P. Karakozov
Adaptive Cardiac Binding: A New Method for Treatment of Dilated Cardiomyopathy
Asian Cardiovasc Thorac Ann, December 1, 2005; 13(4): 351 - 356.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
A. Olsson, F. Bredin, and A. Franco-Cereceda
Echocardiographic findings using tissue velocity imaging following passive containment surgery with the Acorn CorCapTM cardiac support device
Eur. J. Cardiothorac. Surg., September 1, 2005; 28(3): 448 - 453.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Heart FailHome page
T. Tonnessen and C. W. Knudsen
Surgical left ventricular remodeling in heart failure
Eur J Heart Fail, August 1, 2005; 7(5): 704 - 709.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
D. Mancini and D. Burkhoff
Mechanical Device-Based Methods of Managing and Treating Heart Failure
Circulation, July 19, 2005; 112(3): 438 - 448.
[Abstract] [Full Text] [PDF]

Home page
 MMCTSHome page
R. Ascione, P. Wilde, and G. D. Angelini
Left ventricular volume reduction
MMCTS, June 28, 2005; 2005(0628): 760.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
E. N. Soo, R. Ascione, P. Wilde, and G. D. Angelini
Eight years survival after partial left ventriculectomy
Eur. J. Cardiothorac. Surg., April 1, 2005; 27(4): 724 - 725.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
Y. Enomoto, J. H. Gorman III, S. L. Moainie, T. S. Guy, B. M. Jackson, L. M. Parish, T. Plappert, A. Zeeshan, M. G. St. John-Sutton, and R. C. Gorman
Surgical treatment of ischemic mitral regurgitation might not influence ventricular remodeling
J. Thorac. Cardiovasc. Surg., March 1, 2005; 129(3): 504 - 511.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
T. Horii, K. Tambara, K. Nishimura, H. Suma, and M. Komeda
Residual fibrosis affects a long-term result of left ventricular volume reduction surgery for dilated cardiomyopathy in a rat experimental study
Eur. J. Cardiothorac. Surg., December 1, 2004; 26(6): 1174 - 1179.
[Abstract] [Full Text] [PDF]

Home page
 Asian Cardiovasc. Thorac. Ann.Home page
H. B Erdogan, K. Kirali, S. N Omeroglu, D. Goksedef, O. Isik, and C. Yakut
Partial Cardiac Autotransplantation for Reduction of the Left Atrium
Asian Cardiovasc Thorac Ann, June 1, 2004; 12(2): 111 - 114.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. K. Bhudia, P. M. McCarthy, N. G. Smedira, B.-K. Lam, J. Rajeswaran, and E. H. Blackstone
Edge-to-edge (Alfieri) mitral repair: results in diverse clinical settings
Ann. Thorac. Surg., May 1, 2004; 77(5): 1598 - 1606.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
M. J. Jurmann, Y. Weng, T. Drews, M. Pasic, E. Hennig, and R. Hetzer
Permanent mechanical circulatory support in patients of advanced age
Eur. J. Cardiothorac. Surg., April 1, 2004; 25(4): 610 - 618.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
Y. Matsui, Y. Fukada, Y. Naito, and S. Sasaki
Integrated overlapping ventriculoplasty combined with papillary muscle plication for severely dilated heart failure
J. Thorac. Cardiovasc. Surg., April 1, 2004; 127(4): 1221 - 1223.
[Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
T. Koyama, K. Nishimura, Y. Soga, O. Unimonh, and M. Komeda
Reply to the Editor
J. Thorac. Cardiovasc. Surg., December 1, 2003; 126(6): 2110 - 2111.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. M. Setser, R. D. White, B. Sturm, P. M. McCarthy, R. C. Starling, J. B. Young, J. Kasper, T. Buda, N. Obuchowski, and M. L. Lieber
Noninvasive assessment of cardiac mechanics and clinical outcome after partial left ventriculectomy
Ann. Thorac. Surg., November 1, 2003; 76(5): 1576 - 1585.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. C. Gorman and J. H. Gorman III
Does repair of ischemic mitral regurgitation help?
Ann. Thorac. Surg., November 1, 2003; 76(5): 1775 - 1776.
[Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. M. Setser, J. M. Kasper, M. L. Lieber, R. C. Starling, P. M. McCarthy, and R. D. White
Persistent abnormal left ventricular systolic torsion in dilated cardiomyopathy after partial left ventriculectomy
J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 48 - 55.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
K.-l. He, J. Shimizu, G.-h. Yi, A. Gu, M. A. Kashem, D. L. Crabbe, S. Popilskis, E. X. Wu, W. P. Santamore, D. Melvin, et al.
Left ventricular systolic performance in failing heart improved acutely by left ventricular reshaping
J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 56 - 65.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
L. F. P. Moreira, A. Benicio, F. Bacal, E. A. Bocchi, N. A.G. Stolf, and S. A. Oliveira
Determinants of long-term mortality of current palliative surgical treatment for dilated cardiomyopathy
Eur. J. Cardiothorac. Surg., May 1, 2003; 23(5): 756 - 764.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
T. Koyama, K. Nishimura, Y. Soga, O. Unimonh, K. Ueyama, and M. Komeda
Importance of preserving the apex and plication of the base in left ventricular volume reduction surgery
J. Thorac. Cardiovasc. Surg., March 1, 2003; 125(3): 669 - 677.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. Burkhoff
New heart failure therapy: The shape of things to come?
J. Thorac. Cardiovasc. Surg., March 1, 2003; 125(90030): S50 - 52.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
D. Marelli, H. Laks, J. A. Kobashigawa, J. Bresson, A. Ardehali, F. Esmailian, M. D. Plunkett, and B. Kubak
Seventeen-year experience with 1,083 heart transplants at a single institution
Ann. Thorac. Surg., November 1, 2002; 74(5): 1558 - 1567.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
B. M. Jackson, J. H. Gorman III, S. L. Moainie, T. S. Guy, N. Narula, J. Narula, M. G. St. John-Sutton, L. H. Edmunds Jr, and R. C. Gorman
Extension of borderzone myocardium in postinfarction dilated cardiomyopathy
J. Am. Coll. Cardiol., September 18, 2002; 40(6): 1160 - 1167.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. L. Moainie, J. H. Gorman III, T. S. Guy, F. W. Bowen III, B. M. Jackson, T. Plappert, N. Narula, M. G. St. John-Sutton, J. Narula, L. H. Edmunds Jr, et al.
An ovine model of postinfarction dilated cardiomyopathy
Ann. Thorac. Surg., September 1, 2002; 74(3): 753 - 760.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
P. M. McCarthy, A. Franco-Cerceda, E. H. Blackstone, K. Hoercher, J. A. White, J. B. Young, and R. C. Starling
A question of terminology
J. Thorac. Cardiovasc. Surg., April 1, 2002; 123(4): 830 - 830.
[Full Text]

Home page
 Eur. J. Cardiothorac. Surg.Home page
M. Murtra
The adventure of cardiac surgery
Eur. J. Cardiothorac. Surg., February 1, 2002; 21(2): 167 - 180.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
Task Force for the Diagnosis and Treatment of Chro, W. J. Remme, and K. Swedberg
Guidelines for the diagnosis and treatment of chronic heart failure
Eur. Heart J., September 1, 2001; 22(17): 1527 - 1560.
[PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. Burkhoff
New heart failure therapy: The shape of things to come?
J. Thorac. Cardiovasc. Surg., September 1, 2001; 122(3): 421 - 423.
[Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
P. M. McCarthy, M. Takagaki, Y. Ochiai, J. B. Young, T. Tabata, T. Shiota, J. X. Qin, J. D. Thomas, T. J. Mortier, R. F. Schroeder, et al.
Device-based change in left ventricular shape: A new concept for the treatment of dilated cardiomyopathy
J. Thorac. Cardiovasc. Surg., September 1, 2001; 122(3): 482 - 490.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2001 by The American Association for Thoracic Surgery.