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J Thorac Cardiovasc Surg 2001;122:234-241
© 2001 The American Association for Thoracic Surgery

Surgery for Congenital Heart Disease (CHD)

Early and late results of operations for defects associated with corrected transposition and other anomalies with atrioventricular discordance in a pediatric population

From the Department of Pediatric and Adolescent Medicine, Section of Pediatric Cardiology,^a Division of Cardiovascular Diseases and Internal Medicine,^b Section of Biostatistics,^c and Division of Cardiovascular and Thoracic Surgery,^d Mayo Clinic, Rochester, Minn.

Received for publication June 29, 2000. Revisions requested Aug 24, 2000; revisions received Dec 27, 2000. Accepted for publication Feb 12, 2001. Address for reprints: R. H. Feldt, MD, 200 First St, SW, Rochester, MN 55905 (E-mail: feldt.robert{at}mayo.edu).

Abstract

Objectives: The purpose of this study was to determine the early and late results for children having operations for defects associated with corrected transposition of the great arteries and other anomalies with atrioventricular discordance.
Methods: Data on 111 children operated on from July 1, 1971, through January 31, 1996, including clinic records, operative reports, and follow-up visits and questionnaires, were analyzed with particular reference to variables associated with early and late mortality, reoperations, ventricular function, and status of the atrioventricular valves.
Results: Complex associated anomalies were common and included double-outlet right ventricle (n = 43) and situs abnormalities (n = 38). Overall early mortality was 16%; for the 29 patients operated on after 1986, early mortality was 3%. Early survival was adversely affected by patch repair of ventricular septal defect and early operative interval. Follow-up of the 93 early survivors extended to 26.5 years (mean 11.4 years). Overall survival was 77% (±4%) at 5 years and 67% (±5%) at 10 years. Late survival was adversely affected by prior operations, more severe preoperative functional class, and cardiac rhythm other than sinus. Reoperation was required for 38 (41%) patients, most commonly for conduit replacement (n = 22) or repair/replacement of the systemic ventricle atrioventricular valve (n = 13).
Conclusions: These results can serve as a basis for comparison with newer surgical alternatives proposed for corrected transposition of the great arteries.

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