| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Thorac Cardiovasc Surg 2002;123:631-639
© 2002 The American Association for Thoracic Surgery
Surgery for Congenital Heart Disease (CHD) |
From the Departments of Cardiovascular Surgerya and Neuroepidemiology,b Children's Hospital, and the Department of Surgery,c Harvard Medical School, Boston, Mass.
Received for publication June 28, 2001. Revisions requested July 27, 2001; revisions received Aug 2, 2001. Accepted for publication Aug 7, 2001. Address for reprints: Joseph M. Forbess, MD, Department of Cardiovascular Surgery, Children's Hospital, 300 Longwood Ave, Boston, MA 02115 (E-mail: forbess{at}cardio.tch.harvard.edu).
Objective: This study was undertaken to assess neurodevelopment of children after biventricular repair of congenital heart defects.
Methods: Full-scale, performance, and verbal IQs of 69 patients who had undergone biventricular repair were assessed at 5 years of age with the Wechsler Preschool and Primary Scales of Intelligence-Revised. The Wide Range Assessment of Visual-Motor Abilities was used to measure visual-motor skills. Regression analyses adjusting for parental IQ and socioeconomic status were used to evaluate outcome predictors.
Results: Median age at repair was 91 days (range 1-1558 days). Hypothermic circulatory arrest was used in 35 cases (mean duration of hypothermic circulatory arrest 33 ± 17 minutes). Mean full-scale, performance, and verbal IQs for the entire study population were within the reference range (full-scale 96.9 ± 15.9, performance 96.6 ± 16.8, verbal 97.7 ± 15.2). Anatomic diagnosis, age at operation, and use of hypothermic circulatory arrest did not influence full-scale IQ (P = .66, P = .14, and P = .46, respectively), performance IQ (P = .64, P = .36, and P = .73, respectively), or verbal IQ (P = .74, P = .08, and P = .39, respectively). Among patients subjected to hypothermic circulatory arrest, duration of arrest was evaluated as a predictor of outcome. After adjustment for parental IQ, full-scale (P = .12), performance (P = .07), and verbal (P = .22) IQ scores of patients with more than 39 minutes of hypothermic circulatory arrest were not different from those of patients who had arrest periods of 39 minutes or less. After adjustment for socioeconomic status, however, full-scale (P = .05) and performance (P = .03) IQ scores were lower among patients who had more than 39 minutes of hypothermic circulatory arrest. After adjustment for either parental IQ or socioeconomic status, patients with more than 39 minutes of arrest had lower scores on Wide Range Assessment of Visual-Motor Abilities subtests of visual-motor and fine motor abilities and on several performance IQ subtests.
Conclusions: IQs of patients who had undergone biventricular repair of congenital heart defects were within the reference range. However, hypothermic circulatory arrest for longer than 39 minutes was associated with deficits in visual-motor and fine motor skills and possibly in full-scale IQ.
This article has been cited by other articles:
|
|
 |
|
  A. Farouk, M. Karimi, M. Henderson, J. Ostrowsky, E. Siwik, and H. Hennein Cerebral regional oxygenation during aortic coarctation repair in pediatric population. Eur. J. Cardiothorac. Surg., July 1, 2008; 34(1): 26 - 31. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Uzark, K. Jones, J. Slusher, C. A. Limbers, T. M. Burwinkle, and J. W. Varni Quality of Life in Children With Heart Disease as Perceived by Children and Parents Pediatrics, May 1, 2008; 121(5): e1060 - e1067. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Wernovsky Improving neurologic and quality-of-life outcomes in children with congenital heart disease: Past, present, and future J. Thorac. Cardiovasc. Surg., February 1, 2008; 135(2): 240 - 242. [Full Text] [PDF]
|
|
|
|
|
|
D. E. Creighton, C. M.T. Robertson, R. S. Sauve, D. M. Moddemann, G. Y. Alton, A. Nettel-Aguirre, D. B. Ross, I. M. Rebeyka, and and the Western Canadian Complex Pediatric Therapi Neurocognitive, Functional, and Health Outcomes at 5 Years of Age for Children After Complex Cardiac Surgery at 6 Weeks of Age or Younger Pediatrics, September 1, 2007; 120(3): e478 - e486. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. A. Karsdorp, W. Everaerd, M. Kindt, and B. J.M. Mulder Psychological and Cognitive Functioning in Children and Adolescents with Congenital Heart Disease: A Meta-Analysis J. Pediatr. Psychol., June 1, 2007; 32(5): 527 - 541. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Y. Alton, C. M.T. Robertson, R. Sauve, A. Divekar, A. Nettel-Aguirre, S. Selzer, A. R. Joffe, I. M. Rebeyka, D. B. Ross, and Western Canadian Complex Pediatric Therapies Proje Early childhood health, growth, and neurodevelopmental outcomes after complete repair of total anomalous pulmonary venous connection at 6 weeks or younger J. Thorac. Cardiovasc. Surg., April 1, 2007; 133(4): 905 - 911. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. H. Hovels-Gurich, K. Konrad, D. Skorzenski, B. Herpertz-Dahlmann, B. J. Messmer, and M.-C. Seghaye Attentional Dysfunction in Children After Corrective Cardiac Surgery in Infancy Ann. Thorac. Surg., April 1, 2007; 83(4): 1425 - 1430. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. T. Hussain, A. Bhan, S. Sapra, R. Juneja, S. Das, and S. Sharma The bidirectional cavopulmonary (Glenn) shunt without cardiopulmonary bypass: is it a safe option? Interactive CardioVascular and Thoracic Surgery, February 1, 2007; 6(1): 77 - 82. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. J. Visconti, D. Rimmer, K. Gauvreau, P. del Nido, J. E. Mayer Jr, I. Hagino, and F. A. Pigula Regional Low-Flow Perfusion Versus Circulatory Arrest in Neonates: One-Year Neurodevelopmental Outcome Ann. Thorac. Surg., December 1, 2006; 82(6): 2207 - 2213. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. H. Hovels-Gurich, K. Konrad, D. Skorzenski, C. Nacken, R. Minkenberg, B. J. Messmer, and M.-C. Seghaye Long-Term Neurodevelopmental Outcome and Exercise Capacity After Corrective Surgery for Tetralogy of Fallot or Ventricular Septal Defect in Infancy. Ann. Thorac. Surg., March 1, 2006; 81(3): 958 - 966. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. L. Hanley Religion, politics...deep hypothermic circulatory arrest J. Thorac. Cardiovasc. Surg., November 1, 2005; 130(5): 1236 - 1236. [Full Text] [PDF]
|
|
|
|
|
|
W. T. Mahle, K. Lundine, K. R. Kanter, J. M. Forbess, P. Kirshbom, S. R. Tosone, and R. N. Vincent The short term effects of cardiopulmonary bypass on neurologic function in children and young adults Eur. J. Cardiothorac. Surg., November 1, 2004; 26(5): 920 - 925. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-H. Yeh, Y.-C. Wang, Y.-C. Wu, Y.-M. Lin, and P. J. Lin Ischemic preconditioning or heat shock pretreatment ameliorates neuronal apoptosis following hypothermic circulatory arrest J. Thorac. Cardiovasc. Surg., August 1, 2004; 128(2): 203 - 210. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. G. Williams, B. W. McCrindle, D. A. Ashburn, R. A. Jonas, C. Mavroudis, E. H. Blackstone, and the members of the Congenital Heart Surgeon's Soci Outcomes of 829 neonates with complete transposition of the great arteries 12-17 years after repair Eur. J. Cardiothorac. Surg., July 1, 2003; 24(1): 1 - 10. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. L. Stavinoha, D. E. Fixler, and L. Mahony Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children Circulation, June 3, 2003; 107(21): 2722 - 2725. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
