JTCS Speed Up Your Browser
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Pallav J. Shah
James Tatoulis
Brian F. Buxton
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shah, P. J.
Right arrow Articles by Buxton, B. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shah, P. J.
Right arrow Articles by Buxton, B. F.
Related Collections
Right arrow Valve disease

J Thorac Cardiovasc Surg 2003;126:1972-1977
© 2003 The American Association for Thoracic Surgery

Surgery for acquired cardiovascular disease

Factors affecting saphenous vein graft patency: clinical and angiographic study in 1402 symptomatic patients operated on between 1977 and 1999

Pallav J. Shah, MBBS, MS, MCha, Ian Gordon, MSc, PhD, AStatb, John Fuller, MBBS, FRCP (Edin), FRACPc, Siven Seevanayagam, MBBS (Hons), FRACSa, Alex Rosalion, MBBS, FRACSa, James Tatoulis, MBBS, FRACSc, Jai S. Raman, MB, BS, MMed, FRACS, PhDa, Brian F. Buxton, MB, MS, FRACS, FRCS, FRCS(C)a,*

a Department of Cardiac Surgery, Austin Hospital, Melbourne, Victoria, Australia
b Statistical Consulting Centre, University of Melbourne, Parkville, Victoria, Australia
c Epworth Medical Centre, Melbourne, Victoria, Australia

Received for publication December 19, 2002; revisions received May 21, 2003; accepted for publication June 5, 2003.

* Address for correspondence: Brian F. Buxton, MB, MS, FRACS, FRCS, FRCS(C), Austin Hospital, Studley Road, Heidelberg, Victoria, 3084 Australia
brian.buxton{at}austin.org.au

BACKGROUND: The purpose of this study was to find the preoperative and intraoperative factors that affect vein graft patency.

METHODS: A total of 3715 graft angiograms in 1607 patients were studied for recurrence of angina. The preoperative patient characteristics and intraoperative variables were prospectively collected from patients who had primary coronary artery bypass grafting during the period from 1977 to 1999. A total of 1339 (83%) patients were male, with a mean age of 59 years. The mean period from operation to reangiogram was 99 months. The saphenous vein was grafted to the left anterior descending artery in 557 (15%), to the diagonal artery in 669 (18%), to the obtuse marginal artery in 1300 (35%), to the right coronary artery in 409 (11%), and to the posterior descending artery in 780 (21%) cases. Graft failure was defined as >=80% stenosis.

RESULTS: During the course of the study, 2266 (61%) grafts were patent, and 1449 (39%) had failed. The patient variables that significantly reduced graft patency were a younger age (P < .001) and an ejection fraction <30% (P = .047). Operative variables associated with reduced graft patency were small coronary artery diameter (P < .001), large conduit diameter (P = .001), and the coronary artery grafted (lowest patency in the right coronary artery and maximum patency in the left anterior descending artery territory; P = .002). The interval from operation to repeat angiogram (P < .001, with 78% patent at 1 year, 78% at 5 years, 60% at 10 years, and 50% at 15 years) and the year in which the operation was performed (more recent operations had better patency; P < .001) significantly affected graft patency.

CONCLUSIONS: Saphenous vein graft patency improved over the course of the study. The best results were obtained in older patients with good left ventricular function. Large-caliber arteries on the left system, when grafted with a small-diameter vein, were associated with the best outcome.

Keywords: 23,18




This article has been cited by other articles:


Home page
 J. Thorac. Cardiovasc. Surg.Home page
K.-B. Kim, K. R. Cho, and D. S. Jeong
Midterm angiographic follow-up after off-pump coronary artery bypass: serial comparison using early, 1-year, and 5-year postoperative angiograms.
J. Thorac. Cardiovasc. Surg., February 1, 2008; 135(2): 300 - 307.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
P. A.R. Hayward and B. F. Buxton
Contemporary Coronary Graft Patency: 5-Year Observational Data From a Randomized Trial of Conduits
Ann. Thorac. Surg., September 1, 2007; 84(3): 795 - 799.
[Abstract] [Full Text] [PDF]

Home page
 Asian Cardiovasc. Thorac. Ann.Home page
Y. J. Loh, M. Nakao, W. D. Tan, C. H. Lim, Y. S. Tan, and Y. L. Chua
Factors Influencing Radial Artery Size
Asian Cardiovasc Thorac Ann, August 1, 2007; 15(4): 324 - 326.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
N. D. Desai, C. D. Naylor, A. Kiss, E. A. Cohen, R. Feder-Elituv, S. Miwa, S. Radhakrishnan, J. Dubbin, L. Schwartz, S. E. Fremes, et al.
Impact of Patient and Target-Vessel Characteristics on Arterial and Venous Bypass Graft Patency: Insight From a Randomized Trial
Circulation, February 13, 2007; 115(6): 684 - 691.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
T. Schachner, G. Laufer, and J. Bonatti
In vivo (animal) models of vein graft disease.
Eur. J. Cardiothorac. Surg., September 1, 2006; 30(3): 451 - 463.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. Mizukami, T. Sueda, H. Wada, K. Imai, M. Hamamoto, and D. Futagami
Right Gastroepiploic Artery Grafting for Saphenous Vein Graft Pseudoaneurysm
Ann. Thorac. Surg., August 1, 2006; 82(2): 742 - 744.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
S. M. Wildhirt, B. Voss, F. von Canal, M. Benz, J. B. Grammer, R. Bauernschmitt, P. Tassani, and R. Lange
Graft function, histopathology and morphometry of radial arteries used as conduits for myocardial revascularization in patients beyond age 70.
Eur. J. Cardiothorac. Surg., August 1, 2006; 30(2): 333 - 340.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. S.R. Souza, B. Johansson, L. Bojo, R. Karlsson, H. Geijer, D. Filbey, L. Bodin, M. Arbeus, and M. R. Dashwood
Harvesting the saphenous vein with surrounding tissue for CABG provides long-term graft patency comparable to the left internal thoracic artery: Results of a randomized longitudinal trial.
J. Thorac. Cardiovasc. Surg., August 1, 2006; 132(2): 373 - 378.e5.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K.-B. Kim, K. R. Cho, J.-S. Choi, and H.-J. Lee
Right Gastroepiploic Artery for Revascularization of the Right Coronary Territory in Off-Pump Total Arterial Revascularization: Strategies to Improve Patency
Ann. Thorac. Surg., June 1, 2006; 81(6): 2135 - 2141.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
S. Wan, A. A. Arifi, M. C.W. Chan, J. H.Y. Yip, C. S.H. Ng, L. T.C. Chow, A. P.C. Yim, and J. Y. Jeremy
Differential, time-dependent effects of perivenous application of fibrin glue on medial thickening in porcine saphenous vein grafts.
Eur. J. Cardiothorac. Surg., May 1, 2006; 29(5): 742 - 746.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
T. Schachner
Pharmacologic inhibition of vein graft neointimal hyperplasia
J. Thorac. Cardiovasc. Surg., May 1, 2006; 131(5): 1065 - 1072.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
K. R. Cho, J.-S. Kim, J.-S. Choi, and K.-B. Kim
Serial angiographic follow-up of grafts one year and five years after coronary artery bypass surgery.
Eur. J. Cardiothorac. Surg., April 1, 2006; 29(4): 511 - 516.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. J. Wilhelm, M. Igual, R. Mury, R. Tavakoli, R. Pescia, B. Vettiger, D. Koller, M. I. Turina, and M. Genoni
Respiratory Dependent Compression of a Venous Bypass: Therapy by Stenting
Ann. Thorac. Surg., November 1, 2005; 80(5): 1904 - 1907.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
B. F. Buxton, M. Durairaj, D. L. Hare, I. Gordon, S. Moten, V. Orford, and S. Seevanayagam
Do Angiographic Results From Symptom-Directed Studies Reflect True Graft Patency?
Ann. Thorac. Surg., September 1, 2005; 80(3): 896 - 901.
[Abstract] [Full Text] [PDF]

Home page
 J Hand Surg Eur VolHome page
R. S. M. DETHMERS and P. HOUPT
Surgical Management of Hypothenar and Thenar Hammer Syndromes: A Retrospective Study of 31 Instances in 28 Patients
J Hand Surg Eur Vol., August 1, 2005; 30(4): 419 - 423.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
P. J. Shah, K. Bui, S. Blackmore, I. Gordon, D. L. Hare, J. Fuller, S. Seevanayagam, and B. F. Buxton
Has the in situ right internal thoracic artery been overlooked? An angiographic study of the radial artery, internal thoracic arteries and saphenous vein graft patencies in symptomatic patients
Eur. J. Cardiothorac. Surg., May 1, 2005; 27(5): 870 - 875.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
K. L. Yun, Y. Wu, V. Aharonian, P. Mansukhani, T. A. Pfeffer, C. F. Sintek, G. S. Kochamba, G. Grunkemeier, and S. Khonsari
Randomized trial of endoscopic versus open vein harvest for coronary artery bypass grafting: Six-month patency rates
J. Thorac. Cardiovasc. Surg., March 1, 2005; 129(3): 496 - 503.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. F. Sabik III, B. W. Lytle, E. H. Blackstone, P. L. Houghtaling, and D. M. Cosgrove
Comparison of Saphenous Vein and Internal Thoracic Artery Graft Patency by Coronary System
Ann. Thorac. Surg., February 1, 2005; 79(2): 544 - 551.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
C. Acar, R. C. Cook, S. G. Raja, S. Hashim, I. Birdi, P. J. Shah, R. A. Baker, J. J. Knight, U. N. Khot, D. T. Friedman, et al.
Letters Regarding Article by Khot et al, "Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts" * Letters Regarding Article by Khot et al, "Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts" * Letters Regarding Article by Khot et al, "Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts" * Letters Regarding Article by Khot et al, "Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts" * Response
Circulation, January 4, 2005; 111(1): e6 - e9.
[Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. Nezic
Reply
J. Thorac. Cardiovasc. Surg., November 1, 2004; 128(5): 800 - 801.
[Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
P. J. Shah, M. Durairaj, I. Gordon, J. Fuller, A. Rosalion, S. Seevanayagam, J. Tatoulis, and B. F. Buxton
Factors affecting patency of internal thoracic artery graft: clinical and angiographic study in 1434 symptomatic patients operated between 1982 and 2002
Eur. J. Cardiothorac. Surg., July 1, 2004; 26(1): 118 - 124.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. H. Jones
The year in cardiovascular surgery
J. Am. Coll. Cardiol., May 5, 2004; 43(9): 1706 - 1714.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2003 by The American Association for Thoracic Surgery.