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Simon K. Ashiku
Akin Kuzucu
Hermes C. Grillo
Cameron D. Wright
John C. Wain
Douglas J. Mathisen
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Right arrow Trachea and bronchi

J Thorac Cardiovasc Surg 2004;127:99-107
© 2004 The American Association for Thoracic Surgery


General thoracic surgery

Idiopathic laryngotracheal stenosis: Effective definitive treatment with laryngotracheal resection

Simon K. Ashiku, MDa,*, Akin Kuzucu, MDa, Hermes C. Grillo, MDa, Cameron D. Wright, MDa, John C. Wain, MDa, Bruce Lo, MDa, Douglas J. Mathisen, MDa

a Division of Thoracic Surgery, Massachusetts General Hospital, Boston, Mass, USA

Read at the Eighty-second Annual Meeting of The American Association for Thoracic Surgery, Washington, DC, May 5-8, 2002.

Received for publication May 20, 2002; revisions received November 5, 2002; accepted for publication November 14, 2002.

* Address for reprints: Dr Douglas J. Mathisen, Massachusetts General Hospital, Blake 1570, 55 Fruit St, Boston, MA 02214, USA

OBJECTIVE: Little was known about idiopathic laryngotracheal stenosis when it was first described. We have operated on 73 patients with idiopathic laryngotracheal stenosis, have confirmed its mode of presentation and response to surgical therapy, and have established long-term follow-up.

METHODS: Charts of 73 patients treated surgically for idiopathic laryngotracheal stenosis between 1971 and 2002 were retrospectively reviewed.

RESULTS: All patients were treated with a single-staged laryngotracheal resection, with (36/73) and without (37/73) a posterior membranous tracheal wall flap. Nearly all were women (71/73), with a mean age of 46 years (range, 13-74 years). Twenty-eight (38%) of 73 had undergone a previous procedure with laser, dilation, tracheostomy, T-tube, or laryngotracheal operations. After laryngotracheal resection, the majority of patients (67/73) were extubated in the operating room, and 7 required temporary tracheostomies, only 1 of whom was among the last 30 patients. All were successfully decannulated. There was no perioperative mortality. Principal morbidity was alteration of voice quality, which was mild and tended to improve with time. Sixty-seven (91%) of 73 patients had good to excellent long-term results with voice and breathing quality and do not require further intervention for their idiopathic laryngotracheal stenosis.

CONCLUSION: Idiopathic laryngotracheal stenosis is an entity that occurs almost exclusively in women and is without a known cause. It is not a progressive process, but the timing of the operation is crucial. Single-staged laryngotracheal resection is successful in restoring the airway while preserving voice quality in more than 90% of patients. Protective tracheostomy is now rarely required (1/30). Long-term follow-up shows a stable airway and improvement in voice quality.





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