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J Thorac Cardiovasc Surg 2004;127:1421-1426
© 2004 The American Association for Thoracic Surgery

Evolving technology

Early bypass occlusion after deployment of Nitinol connector devices

^a Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland

Received for publication July 21, 2003; revisions received December 21, 2003; accepted for publication January 13, 2004.

^* Address for reprints: Oliver Reuthebuch, MD, Clinic for Cardiovascular Surgery, University Hospital Zurich, Raemistrasse 100, 8044 Zurich, Switzerland
oliver.reuthebuch{at}chi.usz.ch

BACKGROUND: Reducing the negative side effects associated with extracorporeal circulation is the major advantage of off-pump revascularization. However, side clamping of a calcified aorta for proximal anastomoses can cause emboli, resulting in neurologic damage. This problem has been addressed by introducing a mechanical anastomosis device (Symmetry, St Jude Medical) that allows vein-to-aorta anastomosis without manipulating the aorta. This report describes our experience with this device.

METHODS: Between June 2001 and April 2002, 77 connectors (1.3 per patient) were deployed in 61 patients (51 men and 10 women; mean age, 68 ± 8.6 years) undergoing off-pump coronary artery bypass grafting or beating-heart revascularization. Intraoperative quality assessment included transit-time flow measurement (Medistim) and indocyanine green–based angiography (Spy, Novadaq).

RESULTS: The surgeons were meticulously trained in loading of the device. No postoperative neurologic deficits were detected. Fifty-three patients had an uneventful course. However, 8 (13.1%) patients with 12 implanted connectors were symptomatic within 8 months (1 day to 8 months). Angiography revealed significant (95%) stenosis or even occlusion of the proximal vein-to-aorta anastomosis at the level of all connectors. Four patients underwent reoperation (2 dilated-stented and 2 treated with drugs).

CONCLUSION: On the basis of these observations, the routine use of the connector was halted at our institution. At the moment, the use of this therapy is reserved for patients with severely calcified aortas with no technical alternative. Further investigations appear necessary to evaluate the clinical patterns of this otherwise promising technology.

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