HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Serri, K. Articles by Basmadjian, A.J. Search for Related Content PubMed PubMed Citation Articles by Serri, K. Articles by Basmadjian, A.J. Related Collections Coronary disease Electrophysiology - arrhythmias Valve disease Related Article

J Thorac Cardiovasc Surg 2006;131:565-573
© 2006 The American Association for Thoracic Surgery

Surgery for Acquired Cardiovascular Disease

Is a good perioperative echocardiographic result predictive of durability in ischemic mitral valve repair?

Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada

Read at the Eighty-fifth Annual Meeting of The American Association for Thoracic Surgery, San Francisco, Calif, April 10-13, 2005.

Received for publication July 7, 2005; revisions received October 10, 2005; accepted for publication October 20, 2005.

^_* Address for reprints: A. J. Basmadjian, MD, MSc, Montreal Heart Institute, Research Center, 5000 Belanger, Montreal, Quebec, Canada, H1T 1C8 (Email: arsene.basmadjian{at}icm-mhi.org).

BACKGROUND: Chronic ischemic mitral regurgitation is associated with poor long-term survival. Despite the increasing popularity of valve repair, its durability and long-term outcome for ischemic mitral regurgitation have recently been questioned.

METHODS: Seventy-eight patients underwent repair for ischemic mitral regurgitation between 1996 and 2002 at our institution. Of these patients, 73 had complete clinical and echocardiographic follow-up. Preoperative, intraoperative, and postoperative clinical data were obtained, and the results of echocardiograms were reviewed to assess the rate of recurrence of regurgitation after repair and to identify predictive factors.

RESULTS: The mean preoperative mitral regurgitation grade, New York Heart Association class, and left ventricular ejection fraction were 2.72, 2.65, and 39.4%, respectively. Mortality was 12.3% at 30 days and 30.1% at a mean follow-up of 39 ± 25 months. Immediate postoperative echocardiography showed absent or mild mitral regurgitation in 89.4% of patients and showed moderate mitral regurgitation in 10.6%. Freedom from reoperation was 93.2%. Recurrent moderate mitral regurgitation (2+) was present in 36.7% of patients, and severe mitral regurgitation (3+ to 4+) was present in 20.0% at mean follow-up of 28.1 ± 22.5 months. Only age (P = .0130) and less marked preoperative posterior tethering (P = .0362) were predictive of recurrent mitral regurgitation. Patients with a preoperative New York Heart Association class greater than II and recurrent mitral regurgitation greater than 2+ had decreased survival (P = .0152 and P = .0450, respectively).

CONCLUSIONS: Significant recurrent mitral regurgitation occurs following repair for ischemic mitral regurgitation, despite good early results. This finding raises questions about the need for improved repair techniques, better patient selection, or eventual mitral valve replacement in selected patients.

Related Article

Pitfalls and limitations in measuring and interpreting the outcomes of mitral valve repair

David H. Adams and Anelechi Anyanwu
J. Thorac. Cardiovasc. Surg. 2006 131: 523-529. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

				J. Magne, N. Girerd, M. Senechal, P. Mathieu, F. Dagenais, J. G. Dumesnil, E. Charbonneau, P. Voisine, and P. Pibarot Mitral Repair versus Replacement for Ischemic Mitral Regurgitation: Comparison of Short-Term and Long-Term Survival Circulation, September 15, 2009; 120(11_suppl_1): S104 - S111. [Abstract] [Full Text] [PDF]

				F. Onorati, A. S. Rubino, D. Marturano, E. Pasceri, G. Santarpino, S. Zinzi, G. Mascaro, and A. Renzulli Midterm clinical and echocardiographic results and predictors of mitral regurgitation recurrence following restrictive annuloplasty for ischemic cardiomyopathy J. Thorac. Cardiovasc. Surg., September 1, 2009; 138(3): 654 - 662. [Abstract] [Full Text] [PDF]

				N. Piazza, A. Asgar, R. Ibrahim, and R. Bonan Transcatheter Mitral and Pulmonary Valve Therapy J. Am. Coll. Cardiol., May 19, 2009; 53(20): 1837 - 1851. [Abstract] [Full Text] [PDF]

				A. P.-W. Lee, M. Acker, S. H. Kubo, S. F. Bolling, S. W. Park, C. J. Bruce, and J. K. Oh Mechanisms of Recurrent Functional Mitral Regurgitation After Mitral Valve Repair in Nonischemic Dilated Cardiomyopathy: Importance of Distal Anterior Leaflet Tethering Circulation, May 19, 2009; 119(19): 2606 - 2614. [Abstract] [Full Text] [PDF]

				E. Agricola, M. Oppizzi, M. Pisani, A. Meris, F. Maisano, and A. Margonato Ischemic mitral regurgitation: mechanisms and echocardiographic classification Eur J Echocardiogr, March 1, 2008; 9(2): 207 - 221. [Abstract] [Full Text] [PDF]

				P. Kolh Surgical correction of ischaemic mitral regurgitation still a long way to go Eur. Heart J., January 2, 2008; 29(2): 147 - 149. [Full Text] [PDF]

				I. Iglesias Intraoperative TEE Assessment During Mitral Valve Repair for Degenerative and Ischemic Mitral Valve Regurgitation Seminars in Cardiothoracic and Vascular Anesthesia, December 1, 2007; 11(4): 301 - 305. [Abstract] [PDF]

				M. A. Borger, P. M. Murphy, A. Alam, S. Fazel, M. Maganti, S. Armstrong, V. Rao, and T. E. David Initial results of the chordal-cutting operation for ischemic mitral regurgitation J. Thorac. Cardiovasc. Surg., June 1, 2007; 133(6): 1483 - 1492. [Abstract] [Full Text] [PDF]

				F. Vanden Eynden, D. Bouchard, I. El-Hamamsy, A. Butnaru, P. Demers, M. Carrier, L. P. Perrault, J.-C. Tardif, and M. Pellerin Effect of Aortic Valve Replacement for Aortic Stenosis on Severity of Mitral Regurgitation Ann. Thorac. Surg., April 1, 2007; 83(4): 1279 - 1284. [Abstract] [Full Text] [PDF]

				J. Magne, P. Pibarot, F. Dagenais, Z. Hachicha, J. G. Dumesnil, and M. Senechal Preoperative Posterior Leaflet Angle Accurately Predicts Outcome After Restrictive Mitral Valve Annuloplasty for Ischemic Mitral Regurgitation Circulation, February 13, 2007; 115(6): 782 - 791. [Abstract] [Full Text] [PDF]

				Pitfalls and limitations in measuring and interpreting the outcomes of mitral valve repair. J. Thorac. Cardiovasc. Surg., March 1, 2006; 131(3): 523 - 529.