JTCS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Paul C. Lee
Robert J. Korst
Jeffrey L. Port
Nasser K. Altorki
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lee, P. C.
Right arrow Articles by Altorki, N. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lee, P. C.
Right arrow Articles by Altorki, N. K.
Related Collections
Right arrowRelated Article

J Thorac Cardiovasc Surg 2006;132:1382-1388
© 2006 The American Association for Thoracic Surgery

General Thoracic Surgery

Long-term survival and recurrence in patients with resected non–small cell lung cancer 1 cm or less in size

Paul C. Lee, MD, Robert J. Korst, MD, Jeffrey L. Port, MD, Yaniv Kerem, BA, Amanda L. Kansler, MPH, Nasser K. Altorki, MD*

Department of Cardiothoracic Surgery, Weill-Cornell Medical Center, New York, NY.

Read at the Eighty-sixth Annual Meeting of The American Association for Thoracic Surgery, Philadelphia, Pa, April 29-May 3, 2006.

Received for publication April 17, 2006; revisions received August 16, 2006; accepted for publication August 31, 2006.

* Address for reprints: Nasser K. Altorki, MD, Department of Cardiothoracic Surgery, Suite M404, New York Presbyterian Hospital—Weill Medical College of Cornell University, 525 East 68th St, New York, NY 10021 (Email: nkaltork{at}med.cornell.edu).

OBJECTIVE: With the widespread use of computed tomography and the emergence of screening programs, non–small cell lung cancer is increasingly detected in sizes 1 cm or less. We sought to examine the long-term survival and recurrence patterns after resection of these tumors.

METHODS: We conducted a retrospective review over a 15-year period to identify patients with surgically resected non–small cell lung cancer measuring 1 cm or less. Medical records were reviewed, and survival data were analyzed by the Kaplan-Meier method.

RESULTS: There were 83 patients (26 men, 57 women) with a median age of 67 years (range 43-88 years). Median tumor size was 0.90 cm. Lobectomy was performed in 71 patients, bilobectomy in 1, pneumonectomy in 1, segmentectomy in 5, and wedge resection in 5. Postoperative stage was IA in 67 patients, IB in 4, IIA in 1, IIB in 4, IIIA in 2, and IIIB in 5. Median follow-up was 31 months. There was 1 operative death (1.2%). In 5 (31.3%) of the 16 patients with non-IA disease, recurrent cancer developed after resection. No recurrences were observed in the 67 patients with stage IA disease. The 5- and 10-year overall survivals for the entire cohort were 86% and 72%, respectively, and the disease-specific survival was 91% at both time points. For patients with stage IA disease, 5- and 10-year survivals were 94% and 75%, respectively, and the disease-specific survival was 100% at both time points.

CONCLUSION: Eighty-one percent of patients with resected non–small cell lung cancer measuring 1 cm or less had stage IA disease. After surgical resection, recurrence is rare and long-term survival is excellent.

Abbreviations and Acronyms CI = confidence interval; CT = computed tomography; ELCAP = Early Lung Cancer Action Program; NSCLC = non–small cell lung cancer; PET = positron emission tomography


Related Article

Discussion
J. Thorac. Cardiovasc. Surg. 2006 132: 1388-1389. [Extract] [Full Text] [PDF]



This article has been cited by other articles:


Home page
 Interact CardioVasc Thorac SurgHome page
T. Sakuragi, Y. Takeda, T. Teishikata, K. Sakoda, and S. Morita
Is bipolar thermofusion an acceptable option for unseparated interlobar fissure division in pulmonary lobectomy?
Interact CardioVasc Thorac Surg, April 11, 2013; (2013) ivt113v1.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
B. E. Lee, J. L. Port, B. M. Stiles, J. Saunders, S. Paul, P. C. Lee, and N. Altorki
TNM Stage Is the Most Important Determinant of Survival in Metachronous Lung Cancer
Ann. Thorac. Surg., October 1, 2009; 88(4): 1100 - 1105.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
B. A. Whitson, S. S. Groth, S. J. Duval, S. J. Swanson, and M. A. Maddaus
Surgery for Early-Stage Non-Small Cell Lung Cancer: A Systematic Review of the Video-Assisted Thoracoscopic Surgery Versus Thoracotomy Approaches to Lobectomy
Ann. Thorac. Surg., December 1, 2008; 86(6): 2008 - 2018.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
E. L. Grogan, G. J. Stukenborg, A. S. Nagji, W. Simmons, B. D. Kozower, D. R. Jones, and T. M. Daniel
Radiotracer-Guided Thoracoscopic Resection is a Cost-Effective Technique for the Evaluation of Subcentimeter Pulmonary Nodules
Ann. Thorac. Surg., September 1, 2008; 86(3): 934 - 940.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
P. C. Lee, J. L. Port, R. J. Korst, Y. Liss, D. N. Meherally, and N. K. Altorki
Risk Factors for Occult Mediastinal Metastases in Clinical Stage I Non-Small Cell Lung Cancer
Ann. Thorac. Surg., July 1, 2007; 84(1): 177 - 181.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2006 by The American Association for Thoracic Surgery.