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J Thorac Cardiovasc Surg 2007;133:1540-1546
© 2007 The American Association for Thoracic Surgery

Surgery for Congenital Heart Disease

Coarctectomy reduces neoaortic arch obstruction in hypoplastic left heart syndrome

^a Department of Cardiac Surgery, Children’s Hospital Boston, Harvard Medical School, Boston, Mass
^b Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, Boston, Mass.

Read at the Eighty-sixth Annual Meeting of The American Association for Thoracic Surgery, Philadelphia, Pa, April 29-May 3, 2006.

Received for publication April 26, 2006; revisions received December 6, 2006; accepted for publication December 13, 2006.

^_* Address for reprints: Pedro J. del Nido, MD, Department of Cardiac Surgery, Children’s Hospital Boston, 300 Longwood Ave, Bader 273, Boston, MA 02115. (Email: pedro.delnido{at}tch.harvard.edu).

Objective: Neoaortic arch obstruction after stage I palliation is an important risk factor affecting interstage mortality in patients with hypoplastic left heart syndrome, with no accepted standard surgical approach. We sought to determine the efficacy of different techniques for aortic arch reconstruction to reduce the incidence of postoperative neoaortic arch obstruction.

Methods: From January 2000 through June 2005, 210 patients underwent stage I palliation. To enlarge the aortic arch, 12 (6%) patients had a direct connection, 115 (55%) patients had an aortic homograft, 53 (25%) patients had a pulmonary homograft patch, and 30 (14%) patients had autologous pericardium. Independent of the technique for aortic enlargement, 55 (26%) children had coarctectomy.

Results: Eighty patients had a significant arch gradient, as determined by means of echocardiography, and of these, 50 required balloon angioplasty, surgical arch augmentation, or both. Preoperative aortic coarctation was consistently linked to neoaortic arch obstruction (P = .032). Patients having aortic arch enlargement by means of direct connection or with autologous pericardium were less likely to have neoaortic arch obstruction (P = .049). Coarctectomy resulted in a lower incidence of neoaortic arch obstruction, as determined by means of echocardiography (P = .015), or need for reintervention (P = .01).

Conclusions: Patients with hypoplastic left heart syndrome undergoing aortic arch enlargement with autologous tissue are less likely to require intervention for neoaortic arch obstruction compared with those having homograft patch reconstruction. Excision of all ductal tissue by means of coarctectomy reduces the risk of recurrent aortic arch obstruction. An aggressive approach to reconstruction of the arch and the use of autologous tissue at the time of stage I palliation is advocated.

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Discussion
J. Thorac. Cardiovasc. Surg. 2007 133: 1544-1546. [Extract] [Full Text] [PDF]

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