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J Thorac Cardiovasc Surg 2007;134:465-469
© 2007 The American Association for Thoracic Surgery


Surgery for Acquired Cardiovascular Disease

Long-term survival and quality of life of patients with prolonged postoperative intensive care unit stay: Unmasking an apparent success

Mario Gaudino, MDa,*, Fabiana Girola, MDa, Mariantonietta Piscitelli, MDa, Lorenzo Martinelli, MDb, Amedeo Anselmi, MDa, Carmine Della Vellaa, Rocco Schiavello, MDb, Gianfederico Possati, MDa

a Department of Cardiac Surgery, Catholic University, Rome, Italy
b Department of Cardiac Anesthesia, Catholic University, Rome, Italy.

Presented at the Fifth European Association for Cardio-thoracic Surgery/European Society of Thoracic Surgeons Joint Meeting, Stockholm, Sweden, September 9-13, 2006.

Received for publication January 18, 2007; revisions received April 16, 2007; accepted for publication April 20, 2007.

* Address for reprints: Mario Gaudino, MD, Divisione di Cardiochirurgia, Policlinico Universitario A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy. (Email: mgaudino{at}tiscali.it).

Objective: Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (>10 days) postoperative stay in the intensive care unit and were discharged from the hospital.

Methods: Among 3125 consecutive patients who underwent cardiac operations in a 5-year period, we prospectively identified 57 who faced a prolonged postoperative intensive care unit stay and were discharged alive from the hospital. Patients were enrolled in a prospective follow-up protocol and evaluated every 6 to 12 months both clinically and instrumentally.

Results: Mean intensive care unit stay was 34 ± 9 days (range 11–141 days). Follow-up was complete and mean follow-up time was 71 months. Overall survival was 12 (21%) of 57, and the majority of follow-up deaths were cardiac related. Of the surviving patients, only a small minority (4/12) regained full autonomy and returned to their previous lifestyle. Risk factors for prolonged intensive care unit stay were age, New York Heart Association/Canadian Cardiovascular Society class, hypertension, diabetes, low ejection fraction, aortic surgery, preoperative renal failure, nonelective surgery, prolonged cardiopulmonary bypass time, and perioperative use of aortic counterpulsator.

Conclusions: Patients who face a prolonged postoperative intensive care unit stay and who were discharged from the hospital have a very poor long-term outcome and even worse quality of life. These data lead to a consideration of the wisdom of using heroic treatment in patients who face a prolonged postoperative intensive care unit stay in view of the dismal clinical results and enormous use of hospital and human resources.



Abbreviation and Acronym ICU = intensive care unit





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