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Joseph Huh
Danny Chu
S. Chris Malaisrie
Faisal Bakaeen
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J Thorac Cardiovasc Surg 2008;135:648-655
© 2008 The American Association for Thoracic Surgery


General Thoracic Surgery

Utility of detailed preoperative cardiac testing and incidence of post-thoracotomy myocardial infarction

Dawn E. Jaroszewski, MDa,b,c, Joseph Huh, MDa,b, Danny Chu, MDa,b, S. Chris Malaisrie, MDa,b, Anthony D. Riffel, MPASa, Howard S. Gordon, MDa,b, Xing Li Wang, MD, PhDb, Faisal Bakaeen, MDa,b,*

a Michael E. DeBakey Veterans Affairs Hospital, Houston, Tex
b Baylor College of Medicine, Houston, Tex
c Mayo Clinic, Phoenix, Ariz

Received for publication June 19, 2007; revisions received August 20, 2007; accepted for publication September 24, 2007.

* Address for reprints: Faisal Bakaeen, MD, Baylor College of Medicine, Department of Cardiothoracic Surgery, Michael E. DeBakey Veterans Affairs Medical Center, 2002 Holcombe Blvd. OCL (112), Houston, TX 77030. (Email: fbakaeen{at}bcm.edu).

Objective: Recent literature has questioned the efficacy of routine detailed preoperative cardiac ischemia testing and preoperative cardiac intervention before noncardiac surgical procedures.

Methods: We performed a retrospective review of patients undergoing thoracotomy (n = 294) between January of 1999 and January of 2005.

Results: The median age was 62 years. Detailed preoperative cardiac testing was performed on 184 patients (63%) and went beyond a thorough history, physical examination, and electrocardiogram to include at least one of the following: dobutamine stress echo (n = 116), nuclear stress test (n = 66), treadmill test (n = 8), and coronary angiogram (n = 40). Evidence for coronary disease was detected in 43% of tests (99/230) performed. Revascularization was performed in 10% of all patients (4/40) who underwent coronary angiography. Postoperative myocardial infarction occurred in 7 patients (2.4%) with 4 myocardial infarction-related mortalities. No significant difference was found in the incidence of myocardial infarction in patients with (n = 184) or without (n = 110) detailed preoperative cardiac testing (3.3% vs 0.9%, P = .29). Of the 4 patients (1.4%) who underwent revascularization to treat coronary lesions identified during prethoracotomy workup, 2 had a myocardial infarction, 1 of which was caused by thrombosis of a coronary stent. In the subset of patients who underwent lobectomy (n = 149), detailed cardiac testing was performed on 107 patients (72%). The incidence of myocardial infarction was similar in tested and untested patients (2.8% vs 2.4% respectively, P = 1.0).

Conclusion: Selective use of detailed preoperative cardiac testing refines risk stratification and identifies patients for corrective cardiac interventions; however, it did not prove fully protective against myocardial infarction after thoracotomy in our study.



Abbreviations and Acronyms CABG = coronary artery bypass grafting; CAD = coronary artery disease; DSE = dobutamine stress echocardiogram; ECG = electrocardiogram; EST = exercise treadmill stress test; LAD = left anterior descending; MI = myocardial infarction; PTCA = percutaneous transluminal coronary angioplasty; Pthal = Persantine thallium stress test








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