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J Thorac Cardiovasc Surg 2008;135:1153-1158
© 2008 The American Association for Thoracic Surgery

Surgery for Congenital Heart Disease

Ruptured sinus of Valsalva aneurysm: Transaortic repair may cause sinus of Valsalva distortion and aortic regurgitation

^a Division of Pediatric Cardiac Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
^b Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
^c Department of Preventive Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea

Received for publication October 18, 2007; revisions received December 21, 2007; accepted for publication January 3, 2008.

^_* Address for reprints: Tae-Jin Yun, M.D., PhD, Divisional Head, Division of Pediatric Cardiac Surgery, Asan Medical Center, 388-1 Poongnap-dong, Song-pa gu, Seoul, Republic of Korea, 138-736. (Email: tjyun{at}amc.seoul.kr).

Objectives: Recurrent or newly developing aortic regurgitation is a critical problem after the repair of ruptured sinus of Valsalva aneurysm.

Methods: A retrospective review of 56 patients who underwent surgical repair of ruptured sinus of Valsalva aneurysm between June 1990 and August 2006 was performed. Rupture of the right coronary sinus into the right ventricle was the most common anatomic type (39/56, 69.6%). Preoperative aortic regurgitation equal to or greater than grade II (n = 8, 17.9%) was managed by repair (aortic valvuloplasty, n = 5) or replacement (n = 3). Ruptured sinus of Valsalva aneurysm was repaired primarily (n = 7) or by patching (n = 10) through an aortotomy in 17 patients (transaortic group). In the remaining patients (n = 39), ruptured sinus of Valsalva aneurysm was repaired primarily from the chamber into which the corresponding aortic sinus ruptured, and the aneurysmal sac was reinforced with a supporting patch (non-transaortic group).

Results: Median follow-up duration was 46 months (0.4–177 months). There were 2 late deaths. Excluding 3 patients with aortic valve replacement on aneurysm repair, 11 patients (11/53, 21%) had recurrent or new-onset significant aortic regurgitation (II/IV) during the follow-up period. By multivariable analysis, aortic valvuloplasty at initial operation was the only significant risk factor for postoperative aortic regurgitation (P < .001). After adjustment, the non-transaortic approach appeared to be associated with a lower risk of postoperative aortic regurgitation, with marginal significance (hazard ratio 0.28; P = .058). Five-year freedom from significant aortic regurgitation in the transaortic and non-transaortic groups was 68% ± 12% and 94% ± 4%, respectively.

Conclusion: Transaortic repair of ruptured sinus of Valsalva aneurysm may cause postoperative aortic regurgitation by progressive distortion of the aortic sinus geometry.