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J Thorac Cardiovasc Surg 2008;135:1261-1269
© 2008 The American Association for Thoracic Surgery


Surgery for Acquired Cardiovascular Disease

Long-term results of the open stent-grafting technique for extended aortic arch disease

Kazuo Shimamura, MDa, Toru Kuratani, MD, PhDa, Goro Matsumiya, MD, PhDa, Masaaki Kato, MD, PhDd, Yukitoshi Shirakawa, MD, PhDa, Hiroshi Takano, MD, PhDc, Noriyuki Ohta, MD, PhDb, Yoshiki Sawa, MD, PhDa,*

a Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
b Department of Anesthesiology, Osaka University Graduate School of Medicine, Osaka, Japan
c Department of Cardiovascular Surgery, Osaka General Medical Center, Osaka, Japan
d Department of Cardiovascular Surgery, Morinomiya Hospital, Osaka, Japan

Received for publication May 3, 2007; revisions received September 27, 2007; accepted for publication October 31, 2007.

* Address for reprints: Yoshiki Sawa, MD, PhD, Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. (Email: sawa{at}surg1.med.osaka-u.ac.jp).

Objective: This report elucidates the long-term safety and effectiveness of extended aortic arch replacement with an open stent-grafting technique from our 12 years of experience.

Methods: From 1994 to 2004, 126 patients (mean age 67.8 years) with different pathologic conditions of the aortic arch with extension to the descending aorta (57 dissections [acute/chronic = 31/26] and 69 aneurysms) were operated on with an open stent-grafting technique. During deep hypothermic circulatory arrest with selective cerebral perfusion, the stent graft was delivered through the transected proximal aortic arch, and arch replacement with a 4-branched prosthesis was performed.

Results: Operative mortality within 30 days was 3.2%. Perioperative morbidity included 7 (5.6%) strokes and 8 (6.3%) spinal injuries (paraplegia in 3, transient paraparesis in 5). Sixty-three percent of the patients were extubated within 24 hours. In long-term follow-up (mean 60.4 ± 36.5 months, maximum 153 months), survival was 81.1%, 63.3%, and 53.7% at 1, 5, and 8 years. Five (3.9%) late endoleaks were observed but treated with successful additional endovascular repair. Freedom from endoleaks was 98.0%, 91.1%, and 91.1% for 1, 5, and 8 years, respectively.

Conclusion: Long-term observation showed safety and good durability of the open stent-grafting technique for aortic arch disease. This technique could be an attractive treatment option for aortic arch aneurysm with distal extension and aortic dissection requiring aortic arch replacement.



Abbreviations and Acronyms CSFD = cerebrospinal fluid drainage; CT = computed tomography; TEVAR = thoracic endovascular aortic repair; Th = thoracic (vertebra)



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