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J Thorac Cardiovasc Surg 2009;137:60-64
© 2009 The American Association for Thoracic Surgery
Acquired Cardiovascular Disease |
a Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, Tex
b Division of Cardiothoracic Surgery, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Tex
c Section of Adult Cardiac Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Tex
Received for publication June 10, 2008; revisions received August 14, 2008; accepted for publication September 7, 2008. * Address for reprints: Danny Chu, MD, Assistant Professor of Surgery, Division of Cardiothoracic Surgery, Michael E. DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, 2002 Holcombe Blvd, OCL 112, Houston, TX 77030. (Email: dchumd{at}gmail.com).
Objective: Incomplete myocardial revascularization decreases survival for patients undergoing coronary artery bypass grafting. The effects of constructing multiple grafts to each major diseased artery territory are unknown. We aimed to determine the impact on long-term survival after coronary artery bypass grafting of placing multiple grafts to each myocardial territory.
Methods: We reviewed data from 1129 consecutive patients who underwent coronary artery bypass grafting at our institution between 1997 and 2007 and compared outcomes between patients who received multiple grafts to each major diseased artery territory (n = 549) with those of patients who received single grafts to each territory (n = 580). We assessed long-term survival with Kaplan–Meier curves generated by log-rank tests, adjusting for confounding factors with Cox proportional hazards regression analysis.
Results: Patients who received multiple grafts to each major diseased artery territory had longer cardiopulmonary bypass and aortic crossclamp times than patients who received single grafts per territory. Patient groups had similar early outcomes, including 30-day mortalities (1.3% vs 1.4%, P > .999) and incidences of major adverse cardiac events (2.9% vs 2.2%, P = .57). Cox regression 10-year survival curves were also similar between groups (adjusted hazard ratio 0.94, 95% confidence interval 0.67–1.34, P = .74).
Conclusion: Patients who received multiple grafts to each major diseased artery territory had early outcomes similar to those who received single grafts per territory. Constructing multiple grafts to each major diseased artery territory increases operative time and does not improve long-term survival.
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E. Akowuah, S. Theodore, and J. Tatoulis Impact of multiple grafts to each myocardial territory on long-term survival. J. Thorac. Cardiovasc. Surg., August 1, 2009; 138(2): 513 - 513. [Full Text] [PDF] |
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D. Chu and F. G. Bakaeen Reply to the Editor J. Thorac. Cardiovasc. Surg., August 1, 2009; 138(2): 513 - 514. [Full Text] [PDF] |
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