HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Runar Lundblad Odd R. Geiran Jan L. Svennevig Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Lundblad, R. Articles by Svennevig, J. L. Search for Related Content PubMed Articles by Lundblad, R. Articles by Svennevig, J. L. Related Collections Coronary disease Myocardial infarction

J Thorac Cardiovasc Surg 2009;137:862-868
© 2009 The American Association for Thoracic Surgery

Acquired Cardiovascular Disease

Surgical repair of postinfarction ventricular septal rupture: Risk factors of early and late death

^a Department of Thoracic and Cardiovascular Surgery, Rikshospitalet, Oslo, Norway
^b Research Forum, Unit of Clinical Epidemiology and Biostatistics, Ullevål University Hospital, Oslo, Norway
^c Faculty Division, Rikshospitalet, University of Oslo, Oslo, Norway

Received for publication May 30, 2008; revisions received July 20, 2008; accepted for publication September 3, 2008.

^_* Address for reprints: Runar Lundblad, MD, PhD, Department of Thoracic and Cardiovascular Surgery, Rikshospitalet, N-0027 Oslo, Norway. (Email: rulund{at}rikshospitalet.no).

Objective: The aim of the study was to identify risk factors of early and late death after surgical repair of postinfarction ventricular septal rupture.

Methods: During a 25-year period, from May 1981 to August 2006, 102 patients underwent repair of postinfarction ventricular septal rupture. Data were collected on clinical, angiographic, and echocardiographic findings; operative procedures; early morbidity; and survival time. Univariable and multivariable analyses were performed to identify risk factors of 30-day mortality and total mortality.

Results: Thirty-day mortality was 33% altogether and decreased from 45% in the first half to 21% in the second half of the period (P = .01). Follow-up was a mean of 5.2 ± 6.2 years and a median of 2.9 years (range, 0–26.3 years). Five- and 10-year cumulative survival was 50% and 32%, respectively. Shock at surgical intervention and incomplete coronary revascularization were strong and independent risk factors of both 30-day mortality and poor long-term survival.

Conclusions: Early outcome after repair of ventricular septal rupture improved significantly during time, with 30-day mortality being 21% in the last decade. Five- and 10-year cumulative survival was 50% and 32%, respectively. Shock at surgical intervention and incomplete coronary revascularization were strong and independent predictors of poor early and late survival.

This article has been cited by other articles:

				S. Perrotta and S. Lentini In patients undergoing surgical repair of post-infarction ventricular septal defect, does concomitant revascularization improve prognosis? Interactive CardioVascular and Thoracic Surgery, November 1, 2009; 9(5): 879 - 887. [Abstract] [Full Text] [PDF]