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The Journal of Thoracic and Cardiovascular Surgery, Vol 73, 443-448, Copyright © 1977 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
GM Lawrie, GC Morris Jr, DW Chapman, WL Winters and JT Lie
The long-term behavior of vein grafts and their effect on the native
circulation were studied by examining 596 vein grafts in 343 patients at a
mean follow-up of 15.4 months, range zero to 84 months. Serial studies were
performed on 27 patients with 38 grafts. The over-all graft patency rate
was 84 per cent, and the rate after more than 5 years was 89 per cent. The
patency rate in asymptomatic patients was 91 per cent compared with 81 per
cent in the remainder. The patency of grafts attached distal to total
occlusions was 82 per cent (78/82). The angle of origin of the grafts from
the aorta did not appear to influence patency or the severity of intimal
proliferative changes. In 76 patients with 126 grafts, pre- and
postoperative cineangiograms were compared, and changes in the graft and
underlying coronary artery classified as Groups 1 to to 6: Group 1, patent
graft, bidirectional flow in the grafted vessel, proximal lesion unchanged;
Group 2, patent graft, bidirectional flow, proximal lesion progressed to
occlusion locally; Group 3; patent graft, distal flow only, occlusion of
lesion and segment between graft and lesion; Group 4, graft occluded,
native artery unaltered; Group 5, graft occluded, native artery now
occluded at lesion and region of anastomosis; Group 6, new distal lesion.
Results were as follows; Group 1, 58 per cent; Group 2, 21.2 per cent;
Group 3, 5 per cent, Group 4, 12.5 per cent; Group 5, 2.5 per cent; and
Group 6, 0.8 per cent. Native coronary arteries undergoing closure (Group
2) had lesions 95 per cent or greater in 93 per cent of patients. The rate
of closure of ungrafted lesions was 2 per cent. We believe these results
encourage the continued used of vein bypass grafts.
ARTICLES
Patterns of patency of 596 vein grafts up to seven years after aorta- coronary bypass
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