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The Journal of Thoracic and Cardiovascular Surgery, Vol 74, 238-243, Copyright © 1977 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
C Planche, M Weiss and C Verriest
A study of two-stage pulmonary autotransplantation was performed on 29
dogs; 12 dogs died after the first stage, which was always a right lung
reimplantation, and 17 dogs underwent the second stage after varying
intervals of time. In the group of six dogs operated upon with very short
intervals between stages (2 to 8 days) there were no survivors. There were
seven long-term survivors in the subgroup with an interval longer than 4
weeks, and they constitute the largest published series obtained with this
particular procedure. The interval between operative stages was the only
significant controlled variable, as only minor technical or operative
differences were allowed to occur. Ischemia times of the lungs were usually
quite short. The surviving animals were utilized for studies of the
regeneration of the afferent pulmonary nerves (Hering-Breure reflex and
effects of capsaicin) as permitted by a long follow-up period of up to 3
years.
ARTICLES
Two-stage bilateral lung reimplantation in the dog
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J. H. Dark, G. A. Patterson, A. N. Al-Jilaihawi, H. Hsu, T. Egan, and J. D. Cooper Experimental En Bloc Double-Lung Transplantation Ann. Thorac. Surg., October 1, 1986; 42(4): 394 - 398. [Abstract] [PDF] |
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