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The Journal of Thoracic and Cardiovascular Surgery, Vol 76, 483-488, Copyright © 1978 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
DA Murphy, AE Marble, R Landymore and H Dajee
The ability of the hemodynamically isolated dog right atrium to pump
against a resistance equivalent to normal pulmonary artery pressure was
tested in an in vivo preparation. At a preload of 10 mm. Hg, the right
atrium reached a peak systolic pressure of 18.2 mm. Hg (+/- 1.3 S.E.M.)
against an afterload of 12 mm. Hg, but it could eject a flow only
equivalent to 53 percent (+/-6) of the dog's cardiac output (n = 6). At a
preload of 15 mm. Hg, a peak systolic pressure of 21.5 mm. Hg (+/- 0.8) was
recorded against an afterload of 17 mm. Hg, but again, only 55 percent
+/-5) of the dog's cardiac output was ejected. It appears that the cardiac
output from the nonhypertrophied right atrium is limited by the strength of
the right atrial contraction and the physiological limits imposed by the
venous driving pressure.
ARTICLES
Assessment of the isolated right atrium as a pump
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