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The Journal of Thoracic and Cardiovascular Surgery, Vol 77, 310-314, Copyright © 1979 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
DH Tyras, JC Stothert Jr, GC Kaiser, HB Barner, JE Codd and VL Willman
The success of prophylactic digitalization in reducing the incidence of
supraventricular tachyarrhythmias (SVT) was studied in 140 randomly
grouped, consecutive patients undergoing myocardial revascularization
operations. The test group received either 1 or 1.5 mg. of digoxin the day
before operation and were maintained postoperatively on 0.25 mg. of digoxin
daily. There was a significant increase (p less than 0.05) in the incidence
of SVT in the treated patients (17 of 61 or 27.8 percent) vs. the untreated
patients (nine of 79 or 11.4 percent). There was no significant difference
in SVT with the two digitalization dosage levels (31.6 percent with 1 mg.
vs. 21.7 percent with 1.5 mg.). Prophylactic digitalization demonstrates no
benefit in the prevention of SVT following myocardial revascularization and
may, in fact, predispose the patient to these arrhythmias.
ARTICLES
Supraventricular tachyarrhythmias after myocardial revascularization: a randomized trial of prophylactic digitalization
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