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The Journal of Thoracic and Cardiovascular Surgery, Vol 81, 202-211, Copyright © 1981 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
A Chaux, RJ Gray, JM Matloff, H Feldman and H Sustaita
Beginning in March, 1978, 88 patients have had cardiac valve replacements
with St. Jude prostheses. There were 26 males and 62 females, aged 6 to 80
years (mean 60). Single valve replacement was done in 67. Double valve
replacement was done in 21; 12 of them had two St. Jude valves and nine had
a different second valve. There were 57 mitral and 43 aortic valves
replaced. Thirty-six patients had concomitant aorta-coronary bypass, and
six others had additional cardiac procedures. All patients have been
followed for a total of 807 patient-months (mean 9 months). Seventy-nine
have been receiving sodium warfarin and seven are not receiving
anticoagulants. There has been one embolic episode. There are no valve
failures to date. Early mortality is 2.3% and late mortality, 5.7%; no
death was valve related. Fifty- three survivors have improved by two or
more N.Y.H.A. classifications. Fifty-four valves studied postoperatively at
rest, during pacing, and during isoproterenol infusion have demonstrated
significantly better hemodynamic performance than have mitral porcine
xenografts studied in an identical manner (p < 0.05). Phonocardiography,
M-mode and two- dimensional echocardiography, and cinefluoroscopy, carried
out in 18 patients, have proved to be reliable noninvasive techniques for
long- term follow-up. This experience indicates that the St. Jude
prosthesis offers an excellent and predictable alternative in the surgeon's
decision-making concerning valve choices.
ARTICLES
An appreciation of the new St. Jude valvular prosthesis
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