JTCS Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Addetia, A. M.
Right arrow Articles by Callaghan, J. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Addetia, A. M.
Right arrow Articles by Callaghan, J. C.

The Journal of Thoracic and Cardiovascular Surgery, Vol 81, 219-226, Copyright © 1981 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Intramyocardial arteriovenous shunting of blood with nonpulsatile perfusion

AM Addetia and JC Callaghan

Coronary blood drains through three types of channels: the subepicardial veins, the thebesian veins, and the arteriosinusoidal vessels. In this study the changes in the blood draining through the subepicardial and thebesian veins were measured in relation to time, up to 180 minutes. Analysis of the data yielded useful information about the relatively inaccessible microcirculation in the working heart. The first group of eight dogs was subjected to pulsatile perfusion and the second to nonpulsatile perfusion. The arteriovenous oxygen difference decreased at an identical rate of 0.01 ml of oxygen per minute per 100 ml of blood in both groups. Spontaneous increase in drainage (milliliters of blood per 100 gm of myocardium per minute) occurred as follows: Subepicardial venous drainage increased at a rate of 0.34 +/- 0.03 (mean +/- SE) with pulsatile perfusion and at a rate of 0.23 +/- 0.03 with nonpulsatile perfusion; the values were significantly different (p < 0.025). Corresponding values for thebesian venous drainage were 0.08 +/- 0.01 with pulsatile perfusion and 0.06 +/- 0.01 with nonpulsatile perfusion (p < 0.05). As a result, there was a linear increase in total myocardial oxygen utilization (MVO2) with pulsatile perfusion and a decrease with nonpulsatile perfusion. The increase in drainage with nonpulsatile perfusion, therefore, may have been due predominantly to abnormal shunt activity. The difference in drainage increase may then represent nutritive flow, the absence of which led to a fall in MVO2 with nonpulsatile perfusion. There was also some evidence that the "thebesian system" may play a compensatory role during shunting. Abnormal shunting of blood may be partly responsible for the perfusion-related myocardial damage reported in the literature.


This article has been cited by other articles:


Home page
 PerfusionHome page
W.T. Vigneswaran, J.C.S. Pollock, M.P.G. Jamieson, B. Torsney, and G.H. Beastal
Plasma levels of glucose, insulin and cortisol in children undergoing cardiac surgery: effects of pulsatile and nonpulsatile perfusion
Perfusion, January 1, 1989; 4(1): 33 - 39.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1981 by The American Association for Thoracic Surgery.