HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by McNamara, J. J. Articles by Smith, G. T. Search for Related Content PubMed PubMed Citation Articles by McNamara, J. J. Articles by Smith, G. T.

The Journal of Thoracic and Cardiovascular Surgery, Vol 81, 498-501, Copyright © 1981 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Hemorrhagic infarction and coronary reperfusion

JJ McNamara, RV Lacro, M Yee and GT Smith

Coronary ligation experiments were performed on 23 primates. Some of the experiments were followed by reperfusion after periods of occlusion of from 1 to 6 hours. Hemorrhage into the infarct was noted in all animals and was greatest following reperfusion after 4 hours of occlusion or longer. Hemorrhage increases the measured infarct size to the point that it is actually larger than that seen with ligation alone. However, this increase is accounted for by the larger amount of intramyocardial hemorrhage. Hemorrhage is greatest in the center of the infarct and decreases at the margins. It appears that hemorrhage occurs into necrotic muscle and does not occur significantly at the margins of the infarct where damage to otherwise viable myocardium might result.

This article has been cited by other articles:

				S. Premaratne, B. Siu, Wei Zhang, and J. J. McNamara An Evaluation of Streptokinase Therapy in Early Coronary Reperfusion in a Primate Model Angiology, February 1, 1996; 47(2): 107 - 114. [Abstract] [PDF]