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The Journal of Thoracic and Cardiovascular Surgery, Vol 82, 674-683, Copyright © 1981 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
DM Nicoloff, RW Emery, KV Arom, WF Northrup 3d, CR Jorgensen, Y Wang and WG Lindsay
Two hundred thirty-two consecutive patients (October 3, 1977, through
December, 31, 1980) underwent aortic (AVR), mitral (MVR), or double (DVR)
valve replacement with the St. Jude Medical (SJM) prosthesis. Operative
mortality for the entire group was 7.3%. There was 100% follow-up. Warfarin
(Coumadin) anticoagulation was recommended for all patients. There were no
cases of mechanical failure. The incidence of thromboembolism was 0.6/1,000
patient-months for those with AVR, 3/1,000 patient-months for those with
MVR, and 0% for those with DVR. Thrombosis of a prosthesis occurred in two
patients with DVR. Clinically significant hemolysis occurred in three
patients with paravalvar leaks following MVR. Late postoperative prosthetic
infection has not occurred. Postoperative catheterization studies in 33
patients revealed no transvalvular gradient at rest in 21 patients. The
remainder of the patients catheterizd had low transvalvular gradients.
There was a minimal increase in transvalvular gradient with exercise. The
SJM cardiac valve is a viable alternative in the surgical therapy of
valvular heart disease.
ARTICLES
Clinical and hemodynamic results with the St. Jude Medical cardiac valve prosthesis. A three-year experience
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