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The Journal of Thoracic and Cardiovascular Surgery, Vol 83, 52-64, Copyright © 1982 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
D Metras, AO Coulibaly, K Ouattara, J Chauvet, A Ekra, A Longechaud and E Bertrand
Twenty patients with endomyocardial fibrosis (EMF), the largest series
reported to date, were operated upon between June, 1978, and June, 1980.
Eleven were male and nine female, ranging in age from 6 to 23 years (mean
13.3 years). There were seven cases of right ventricular (RVEMF), six of
left ventricular (LVEMF), and seven cases of bilateral EMF. All patients
underwent endocardiectomy and atrioventricular valve replacement with a
xenograft. Four patients had an additional valvular annuloplasty. There
were four postoperative deaths (all bilateral EMF): two from low cardiac
output and one each from hepatic failure and cerebral malaria. There was
one late death from serum hepatitis. The other patients had a relatively
difficult postoperative course, but none of the 20 patients
atrioventricular block. The longest follow-up of the 15 survivors is 28
months (mean 16.7 months). All patients are symptom free. Three take
digitalis and/or diuretics. Ten have been recatheterized from 6 months to 1
year after operation. Intracardiac pressures, the ventricular
cineangiogram, liver, and heart size returned to normal in patients with
LVEMF; in RVEMF, despite clinical improvement, most of these parameters
remained abnormal. Of special interest were (1) our recognitions of an
early type of LVEMF and (2) our surgical preservation of a thin
juxta-annular rim of fibrosis in the right ventricle to avoid
atrioventricular block. Operation is indicated in all patients with LVEMF,
despite greater risk. Early intervention is advised in RVEMF to avoid
irreversible liver damage and cardiac enlargement.
ARTICLES
Endomyocardial fibrosis: early and late results of surgery in 20 patients
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