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The Journal of Thoracic and Cardiovascular Surgery, Vol 83, 306-310, Copyright © 1982 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Early failures of Ionescu-Shiley bioprosthesis after mitral valve replacement in children

Fm Galioto Jr, FM Midgley, S Kapur, LW Perry, DC Watson, SR Shapiro, RN Ruckman and LP Scott 3d

Two infants, 101/2 and 11 1/2 months of age, underwent mitral valve replacement with Ionescu-Shiley bovine bioprosthesis for congenital cardiac defects. Both patients had early valve failure, 19 months and 4 months after implantation, due to the growth of excessive collagen on the ventricular surface of the bioprosthesis with adherence of the collagen primarily to the sewing rings and struts of the valves. The cause of this excessive collagen reaction is unknown. Further study is needed to document the true incidence of this problem.




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Copyright © 1982 by The American Association for Thoracic Surgery.