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The Journal of Thoracic and Cardiovascular Surgery, Vol 84, 367-372, Copyright © 1982 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Malignant fibrous histiocytoma of the mediastinum and lung: a report of three cases

SA Mills, RH Breyer, FR Johnston, AS Hudspeth, RB Marshall, RH Choplin, AR Cordell and RT Myers

One case of primary malignant fibrous histiocytoma of the lung and two cases of that tumor in the mediastinum are reported. Primary malignant fibrous histiocytoma is rare in those areas, appearing more commonly in deep fascia and skeletal muscles of the extremities and torso and in the retroperitoneum. Most of the tumors contain both fibroblast-like and histiocyte-like cells; some contain pleomorphic giant cells and inflammatory cells. They are often confused with other sarcomas, and their true biologic potential is not clearly defined. Radiation appears to be a very useful adjunct to surgical therapy and was used in the cases reported here.


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Resection of malignant fibrous histiocytoma involving the thoracoabdominal aorta with staged emobolization of the intercostal arteries.
J. Thorac. Cardiovasc. Surg., September 1, 2006; 132(3): 681 - 683.
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