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The Journal of Thoracic and Cardiovascular Surgery, Vol 84, 560-568, Copyright © 1982 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Prosthetic replacement for the thoracic vena cava: an experimental study

AC Fiore, JW Brown, RS Cromartie, LC Ofstein, PS Peigh, NS Sears, WP Deschner and H King

The superior vena cava (SVC) and thoracic inferior vena cava (IVC) were replaced in 46 dogs with autologous vein, knitted Dacron, glutaraldehyde-fixed porcine pericardium, unsupported polytetrafluorethylene (PTFE), and externally stented PTFE. After 30 days, patency rates were determined by contrast venography and were 100%, 9%, 50%, 75%, and 100%, respectively. The patency rates of Dacron and glutaraldehyde-fixed pericardium are considered unacceptable when compared to autologous vein (p less than 0.05). Stented PTFE exhibited a patency rate equal to that of autologous vein at 30 days, minimal graft reaction, excellent incorporation by host fibroblasts, and a smooth neointima. The external spiral support added to PTFE enchanced the thromboresistance of this graft in the thoracic venous system. Long- term follow-up is required to determine if the stented PTFE prosthesis remains comparable to autologous vein as a venous conduit.

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