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The Journal of Thoracic and Cardiovascular Surgery, Vol 86, 186-192, Copyright © 1983 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
WF Bria, DJ Kanarek and H Kazemi
Surgical resection of lung cancer is frequently required in patients with
severely impaired lung function resulting from chronic obstructive
pulmonary disease. Twenty patients with obstructive lung disease and cancer
(mean preoperative forced expiratory volume in 1 second [FEV1] = 1.73 L)
were studied preoperatively and postoperatively by spirometry and
radionuclide perfusion, single-breath ventilation, and washout techniques
to test the ability of these methods to predict preoperatively the partial
loss of lung function by the resection. Postoperative FEV1 and forced vital
capacity (FVC) were accurately predicted by the formula: postoperative FEV1
(or FVC) = preoperative FEV1 X percent function of regions of lung not to
be resected (r = 0.88 and 0.95, respectively). Ventilation and perfusion
scans are equally effective in prediction. Washout data add to the
sophistication of the method by permitting the qualitative evaluation of
ventilation during tidal breathing. Criteria for patients requiring the
study are suggested.
ARTICLES
Prediction of postoperative pulmonary function following thoracic operations. Value of ventilation-perfusion scanning
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