JTCS Tips for Better Browsing
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Breyer, R. H.
Right arrow Articles by Cordell, A. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Breyer, R. H.
Right arrow Articles by Cordell, A. R.

The Journal of Thoracic and Cardiovascular Surgery, Vol 86, 338-349, Copyright © 1983 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association

ARTICLES

Is a left ventricular vent necessary for coronary artery bypass operations performed with cardioplegic arrest?

RH Breyer, JW Meredith, SA Mills, A Trillo, ML Barringer, ZK Shihabi, HM Schey and AR Cordell

The need for ventricular venting with hypothermic cardioplegic arrest is controversial. We report an evaluation of the need for left ventricular venting in a canine model that closely simulates conditions during routine coronary artery bypass grafting (CABG). Thirty-five dogs were placed on cardiopulmonary bypass for 60 minutes of hypothermic cardioplegic arrest (18 vented, 17 nonvented) and then reperfused for 30 minutes. Myocardial temperature and left atrial pressure (LAP) were recorded continuously. Before and 30 minutes after hypothermic cardioplegic arrest, left ventricular function curves were generated (six vented, six nonvented), and biopsy specimens of the left ventricle were taken for adenosine triphosphate (ATP) determinations (11 vented, 10 nonvented) and semiquantitative grading of mitochondrial ultrastructure (six vented, six nonvented). LAP in nonvented dogs was 7.4 mm Hg during hypothermic cardioplegic arrest and 5.0 mm Hg during reperfusion. Temperature during hypothermic cardioplegic arrest was 12.3 degrees C in vented dogs and 11.3 degrees C in nonvented dogs (p = 0.5). There were no differences in left ventricular function or preservation of mitochondrial ultrastructure between vented and nonvented dogs. ATP after hypothermic cardioplegic arrest was 96.6% of control (4.30 microM/gm) in vented dogs and 94.6% (4.37 microM/gm) in nonvented dogs (p = 0.7). The absence of left ventricular venting did not lead to ventricular distention or more rapid rewarming. These data in vented dogs and nonvented dogs strongly support the belief that left ventricular venting is not necessary during routine CABG.


This article has been cited by other articles:


Home page
 Card Surg AdultHome page
J. W. Hammon
Extracorporeal Circulation: Perfusion System
Card. Surg. Adult, January 1, 2008; 3(2008): 350 - 370.
[Full Text]

Home page
 Card Surg AdultHome page
E. A. Hessel II and L. H. Edmunds Jr.
Extracorporeal Circulation: Perfusion Systems
Card. Surg. Adult, January 1, 2003; 2(2003): 317 - 338.
[Full Text]

Home page
 Ann. Thorac. Surg.Home page
L. A. Robinson, G. D. Schwarz, D. B. Goddard, W. H. Fleming, and T. A. Galbraith
Myocardial Protection for Acquired Heart Disease Surgery: Results of a National Survey
Ann. Thorac. Surg., February 1, 1995; 59(2): 361 - 372.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1983 by The American Association for Thoracic Surgery.