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The Journal of Thoracic and Cardiovascular Surgery, Vol 86, 616-620, Copyright © 1983 by The American Association for Thoracic Surgery and The Western Thoracic Surgical Association
RS Faro, MD Golden, H Javid, C Serry, GA DeLaria, D Monson, M Weinberg, JA Hunter and H Najafi
Despite a 15 year experience with the aorta-coronary bypass operation,
indications for its use remain unsettled, especially in the elderly.
Between January, 1974, and June, 1980, 2,667 patients underwent coronary
artery revascularization with an overall mortality of 3.8% (101/2,667).
During the last 12 months the mortality has decreased to 1%. There were
2,562 patients below the age of 70, with a mortality of 3.5% (90/2,562), in
contrast to 105 patients over the age of 70, with a mortality of 10.5%
(11/105) (p = 0.002). In patients less than 70 years of age there was a
significant difference between the mortality of men, 3.12% (67/2,146), and
that of women, 5.53% (23/416) (p = 0.015). This disparity of operative risk
was far more pronounced in patients over 70 years of age: men 6% (5/84) and
women 28.6% (6/21) (p = 0.002). The overall operative mortality of women,
6.6% (29/437), was significantly different from the overall mortality of
men, 3.2% (72/2,230) (p = 0.001). An in depth analysis of past medical
history, risk factors, and catheterization data is presented in those
patients over the age of 70. The average number of vessels bypassed was
2.40: men 2.47 and women 2.09 (p = NS). The ages varied from 70 to 81 years
with a mean of 72.5. Smoking (p = 0.012) and diabetes (p = 0.0078) were
significant risk factors for coronary disease. Smoking (p = 0.032) and
abnormal pulmonary artery pressures (p = 0.0429) were significant variables
affecting mortality. A 97.1% follow-up was obtained up to 78 months.
Coronary artery revascularization can be performed in men below the age of
70 with acceptable mortality, but there is a twofold increase above the age
of 70. Women can undergo revascularization below the age of 70 with a
significantly higher risk than males. Those above the age of 70 are at
severe risk and should undergo revascularization only after careful
selection.
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